array(1) { [0]=> object(AppBundle\Entity\geneTOpubmed)#307 (6) { ["id":"AppBundle\Entity\geneTOpubmed":private]=> int(4518) ["geneNihId":"AppBundle\Entity\geneTOpubmed":private]=> int(945) ["pubmedNihId":"AppBundle\Entity\geneTOpubmed":private]=> int(3139766) ["title":"AppBundle\Entity\geneTOpubmed":private]=> string(89) "Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells." ["urltitle":"AppBundle\Entity\geneTOpubmed":private]=> string(87) "isolation-of-a-cdna-encoding-cd33-a-differentiation-antigen-of-myeloid-progenitor-cells" ["content":"AppBundle\Entity\geneTOpubmed":private]=> string(9478) " 3139766 1988 11 09 2012 11 15
0022-1767 141 8 1988 Oct 15 Journal of immunology (Baltimore, Md. : 1950) J. Immunol. Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells. 2797-800 A cDNA clone encoding the human myeloid Ag CD33 was isolated from a U937 cDNA library after three rounds of transient expression in COS cells and enrichment by panning. COS cells transfected with the isolated clone expressed a surface protein recognized by the anti-CD33 mAb MY9, L1B2, and L4F3, having mass similar to but slightly smaller than the mass of CD33 expressed on myeloid cells. CD33 transcripts were found constitutively expressed in several myeloid progenitor cell lines. The cDNA sequence predicts a 40-kDa polypeptide with the typical features of a glycosylated integral membrane protein. The extracellular part of CD33 contains two Ig-like domains which are highly related to the first two domains of the neural cell myelin-associated glycoprotein and the B cell Ag CD22. Simmons D D Department of Molecular Biology, Massachusetts General Hospital, Boston 02114. Seed B B eng GENBANK M23197 PIR UNKNOWN Journal Article Research Support, Non-U.S. Gov't
United States J Immunol 2985117R 0022-1767 0 Antigens, CD 0 Antigens, Differentiation, Myelomonocytic 0 CD33 protein, human 0 Membrane Glycoproteins 0 Sialic Acid Binding Ig-like Lectin 3 9007-49-2 DNA AIM IM Amino Acid Sequence Animals Antigens, CD Antigens, Differentiation, Myelomonocytic genetics isolation & purification Base Sequence Cell Line Cloning, Molecular DNA isolation & purification Genes Genes, Immunoglobulin Haplorhini Hematopoietic Stem Cells analysis Humans Membrane Glycoproteins genetics isolation & purification Molecular Sequence Data Sialic Acid Binding Ig-like Lectin 3 Transfection
1988 10 15 1988 10 15 0 1 1988 10 15 0 0 ppublish 3139766
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