The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Alternative name 1 P2X7, Rat Mab anti-Mouse; Clone: Hano43, FITC conj.Alternative name 2 P2X7, Rat Mab antibody-Mouse; Clone: Hano43, FITC conj.Alternative name 3 P2X7, Rattus norvegicus Mab antibody-Mus musculus; Clone: Hano43, FITC conj.
Alternative name 1 P2X7, Rat Mab anti-Mouse; Clone: Hano43, Alexa 647 conj.Alternative name 2 P2X7, Rat Mab antibody-Mouse; Clone: Hano43, Alexa 647 conj.Alternative name 3 P2X7, Rattus norvegicus Mab antibody-Mus musculus; Clone: Hano43, Alexa 647 conj.
Alternative name 1 P2X7, Rat Mab anti-Mouse; Clone: Hano43, flow,IFAlternative name 2 P2X7, Rat Mab antibody-Mouse; Clone: Hano43, flow,IFAlternative name 3 P2X7, Rattus norvegicus Mab antibody-Mus musculus; Clone: Hano43, flow,IF
Alternative name 1 P2X7, Rat Mab anti-Mouse; Clone: Hano43, Alexa 488 conj.Alternative name 2 P2X7, Rat Mab antibody-Mouse; Clone: Hano43, Alexa 488 conj.Alternative name 3 P2X7, Rattus norvegicus Mab antibody-Mus musculus; Clone: Hano43, Alexa 488 conj.
Alternative name 1 P2X7, Rat Mab anti-Mouse; Clone: Hano43, flow,IFAlternative name 2 P2X7, Rat Mab antibody-Mouse; Clone: Hano43, flow,IFAlternative name 3 P2X7, Rattus norvegicus Mab antibody-Mus musculus; Clone: Hano43, flow,IF
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Gene info The purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) belongs to the family of purinoceptors for ATP (1). This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules (1,2). Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression (2). Recent studies have suggested that P2RX7 may play a key role in immune-mediated diseases such as rheumatoid arthritis (3) as well as neuropsychiatric disorders (4).Gene names P2X purinoceptor 7, P2X7, purinergic receptor P2X ligand-gated ion channel 7Antibodie's label unlabelled serum
Gene info The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.Gene names P2RX7, P2X7Antibodie's label unlabelled serum
Storage For short term storage P2RX7 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the P2RX7 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name purinergic receptor P2X, ligand-gated ion channel, 7 recombinant Protein