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All about genes

F2: coagulation factor II, thrombin

PT, RPRGL2, THPH1

Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Organism: human (Homo sapiens)

F2 related publications

F2 description

15(r)-15-methyl prostaglandin f2alpha methyl ester

Catalog: sc-205029 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 15(R)-15-methyl Prostaglandin F2alpha methyl ester

A lipid-soluble prodrug form of 15(R)-15-methyl PGF2α

cat-1 antibody (f-2)

Catalog: sc-515782 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 CAT-1 Antibody (F-2)

recommended for detection of CAT-1 of human origin by WB, IP, IF and ELISA

cleaved thrombin apii antibody (b-7)

Catalog: sc-398087 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 cleaved Thrombin APII Antibody (B-7)

recommended for detection of cleaved Thrombin APII of mouse, rat and human origin by WB, IP, IF and ELISA

cleaved thrombin apii antibody (g-1)

Catalog: sc-398035 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 cleaved Thrombin APII Antibody (G-1)  cleaved Thrombin APII Antibody (G-1)  cleaved Thrombin APII Antibody (G-1)

recommended for detection of cleaved Thrombin APII of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA

g beta 1 antibody (f-2)

Catalog: sc-515764 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 G beta 1 Antibody (F-2)  G beta 1 Antibody (F-2)  G beta 1 Antibody (F-2)  G beta 1 Antibody (F-2)

recommended for detection of Gβ 1 of mouse, rat and human origin by WB, IP, IF and ELISA

opticin antibody (f-2)

Catalog: sc-271306 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 opticin Antibody (F-2)  opticin Antibody (F-2)

recommended for detection of opticin of mouse, rat and human origin by WB, IP, IF and ELISA

parp-1 antibody (f-2)

Catalog: sc-8007 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 PARP-1 Antibody (F-2)  PARP-1 Antibody (F-2)  PARP-1 Antibody (F-2)  PARP-1 Antibody (F-2)

recommended for detection of full-length PARP-1 and the C-terminal cleavage product of PARP-1 of and human origin by WB, IP, IF, IHC(P) and ELISA

prothrombin antibody (12)

Catalog: sc-136449 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 Prothrombin Antibody (12)  Prothrombin Antibody (12)

recommended for detection of Prothrombin of human origin by WBIP

prothrombin antibody (28h5)

Catalog: sc-69769 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 Prothrombin Antibody (28H5)  Prothrombin Antibody (28H5)

recommended for detection of Prothrombin of human origin by WB, IP and ELISA

prothrombin antibody (ahp-5013)

Catalog: sc-73470 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 Prothrombin Antibody (AHP-5013)  Prothrombin Antibody (AHP-5013)

recommended for detection of Prothrombin, Prethrombin-1 fragment 2 and Meizothrombin of human origin by WB and IP

Anti-human tnf-alpha Catalog: 101-M17 | Size: 500ug | Price: €372.22 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Human (Homo sapiens) Synonyms TNF; DIF; TNFA; TNFSF2; TNF-alpha
Anti-human tnfrsf25 Catalog: 101-M664 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name TNFRSF25 Species Reactivity Human (Homo sapiens) Synonyms TNFRSF25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12
Anti-human eotaxin-2 Catalog: 101-M01 | Size: 500ug | Price: €372.22 Supplier: Reliatech antibodies

Gene Name Eotaxin-2 Species Reactivity Human (Homo sapiens) Synonyms CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24
Anti-human coagulation factor ii Catalog: 101-M330 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name Coagulation Factor II Species Reactivity Human (Homo sapiens) Synonyms MCFD2; F5F8D; SDNSF; F5F8D2; LMAN1IP
Anti-human ccm-2 Catalog: 102-PA26S | Size: 100ug | Price: €216.13 Supplier: Reliatech antibodies

Gene Name CCM-2 Species Reactivity Human (Homo sapiens) Synonyms CCM-2; malcavernin; cerebral cavernous malformation 2; OSM; C7orf22; PP10187
Anti-mouse il-6 Catalog: 103-M424 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name IL-6 Species Reactivity Mouse (Mus musculus) Synonyms Il6; Il-6
Anti-rat il-1 beta Catalog: 104-P04 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name IL-1 beta Species Reactivity Rat (Rattus norvegicus) Synonyms Il1b
Anti-human il-6 Catalog: 102-P153G | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name IL-6 Species Reactivity Human (Homo sapiens) Synonyms IL6; HGF; HSF; BSF2; IL-6; IFNB2
Anti-human il-10 receptor beta Catalog: 101-M473 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name IL-10 receptor beta Species Reactivity Human (Homo sapiens) Synonyms IL10RB; CRFB4; CRF2-4; D21S58; D21S66; CDW210B; IL-10R2
Anti-mouse sf-20 Catalog: 103-P81 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name SF-20 Species Reactivity Mouse (Mus musculus) Synonyms C19orf10; IL25; IL27; SF20; IL27w; R33729_1; EUROIMAGE1875335
Anti-mouse gm-csf Catalog: 103-PA06 | Size: 200ug | Price: €325.39 Supplier: Reliatech antibodies

Gene Name GM-CSF Species Reactivity Mouse (Mus musculus) Synonyms Csf2, Csfgm; GM-CSF; Gm-CSf; MGI-IGM
Anti-human prame Catalog: 102-PA28S | Size: 100ug | Price: €216.13 Supplier: Reliatech antibodies

Gene Name PRAME Species Reactivity Human (Homo sapiens) Synonyms Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; MAPE, OIP4
Anti-mouse tnf-alpha Catalog: 103-PA09S | Size: 100ug | Price: €216.13 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Mouse (Mus musculus) Synonyms Tnf; DIF; Tnfa; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
Anti-mouse tnf-alpha Catalog: 103-PA09 | Size: 200ug | Price: €325.39 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Mouse (Mus musculus) Synonyms Tnf; DIF; Tnfa; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
Anti-mouse gm-csf Catalog: 103-P06 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name GM-CSF Species Reactivity Mouse (Mus musculus) Synonyms Csf2, Csfgm; GM-CSF; Gm-CSf; MGI-IGM
Anti-human gdnf r alpha 4 Catalog: 101-M440 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name GDNF R alpha 4 Species Reactivity Human (Homo sapiens) Synonyms glial cell line derived neurotrophic factor Receptor alpha 4
Anti-human il-1 beta Catalog: 101-M465 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name IL-1 beta Species Reactivity Human (Homo sapiens) Synonyms IL1B; IL-1; IL1F2; IL1-BETA
Anti-mouse tnf-alpha Catalog: 103-P35 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Mouse (Mus musculus) Synonyms Tnf; DIF; Tnfa; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
Anti-human ccl-24 Catalog: 101-M268 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name CCL-24 Species Reactivity Human (Homo sapiens) Synonyms CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24
Anti-human baff Catalog: 101-M18 | Size: 500ug | Price: €372.22 Supplier: Reliatech antibodies

Gene Name BAFF Species Reactivity Human (Homo sapiens) Synonyms TNFSF13B; DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Anti-human fgf-22 Catalog: 101-M407 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name FGF-22 Species Reactivity Human (Homo sapiens) Synonyms FGF22
Anti-mouse il-6 Catalog: 103-P15 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name IL-6 Species Reactivity Mouse (Mus musculus) Synonyms Il6; Il-6
Anti-mouse il-1 beta Catalog: 103-P11 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name IL-1 beta Species Reactivity Mouse (Mus musculus) Synonyms interleukin 1 beta
Anti-mouse serpin f2 Catalog: 103-M471 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name Serpin F2 Species Reactivity Mouse (Mus musculus) Synonyms Serpinf2; Pli; AI747498; Serpimf2
Anti-mouse tnf r1 Catalog: 103-M132 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name TNF R1 Species Reactivity Mouse (Mus musculus) Synonyms Tnfrsf1a; FPF; p55; TNF-R; TNFAR; TNFRI; Tnfr1; p55-R; CD120a; TNF-R1; TNFR60; Tnfr-2; TNF-R-I; TNF-R55; TNFRp55; TNF-alphaR1; TNFalpha-R1
Anti-human fgf-2 (basic) Catalog: 102-P13 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name FGF-2 (basic) Species Reactivity Human (Homo sapiens) Synonyms FGF2; BFGF; FGFB; HBGF-2
Anti-human tnfrsf21 Catalog: 101-M663 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name TNFRSF21 Species Reactivity Human (Homo sapiens) Synonyms TNFRSF21; DR6; CD358; BM-018
Anti-human gm-csf r alpha Catalog: 101-M435 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name GM-CSF R alpha Species Reactivity Human (Homo sapiens) Synonyms Csf2ra; CD116; Csfgmra; GM-CSFR; GM-CSF-Ra
Coxsackievirus type a15 control culture fluid for limit of detection determination and positive control Catalog: 0835144CF | Size: 1 mL | Price: €554.72 Supplier: Natrols and viral diagnostic antigens

More information Caution when handling viruses Viral antigens, culture fluids, DNA controls and samples should only be opened in a BL2 protected laboratory. Infectious viruses are Biologic Safety level 2 organisms. Viral culture fluids are tested for their Tissue Culture Infective Dose or TCID50. we recommend to use titers higher than10*5 U/ml. LOD or limit of detection determinations , IVD Assay development, molecular diagnostics and other viral based IVD assays can be developed with viral antigens, DNAs and fluid viral samples. Intended IVD use Only for research use in virology laboratories with biosafety level 2 rooms. For IVD an ISO 13485 CE certification is needed. Do not use these virus related reagents for production of products witch are mentioned in section 351 of the Public Health Service Act.
Anti-human il-33 Catalog: 102-P238 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name IL-33 Species Reactivity Human (Homo sapiens) Synonyms IL33; DVS27; IL1F11; NF-HEV; NFEHEV; C9orf26; RP11-575C20.2
Anti-human prame Catalog: 102-PA28 | Size: 200ug | Price: €325.39 Supplier: Reliatech antibodies

Gene Name PRAME Species Reactivity Human (Homo sapiens) Synonyms Melanoma antigen preferentially expressed in tumors; Opa-interacting protein 4; MAPE, OIP4
Anti-mouse gm-csf Catalog: 103-PA06AG | Size: 50ug | Price: €231.74 Supplier: Reliatech antibodies

Gene Name GM-CSF Species Reactivity Mouse (Mus musculus) Synonyms Csf2, Csfgm; GM-CSF; Gm-CSf; MGI-IGM
Anti-human tnf-alpha Catalog: 102-P87 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Human (Homo sapiens) Synonyms TNF; DIF; TNFA; TNFSF2; TNF-alpha
Anti-mouse tnf r2 Catalog: 103-M134 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name TNF R2 Species Reactivity Mouse (Mus musculus) Synonyms Tnfrsf1b; p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
Anti-human fgf-2 (basic) Catalog: 102-PA08 | Size: 200ug | Price: €238.94 Supplier: Reliatech antibodies

Gene Name FGF-2 (basic) Species Reactivity Human (Homo sapiens) Synonyms FGF2; BFGF; FGFB; HBGF-2
Anti-human tnf-alpha Catalog: 102-P87G | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Human (Homo sapiens) Synonyms TNF; DIF; TNFA; TNFSF2; TNF-alpha
Anti-human tmeff1 Catalog: 101-M650 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name TMEFF1 Species Reactivity Human (Homo sapiens) Synonyms TMEFF1; TR-1; H7365; C9orf2; CT120.1
Anti-human follistatin like-protein 1 Catalog: 101-M422 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

Gene Name Follistatin like-protein 1 Species Reactivity Human (Homo sapiens) Synonyms FST; FS
Anti-rat tnf-alpha Catalog: 104-P11 | Size: 100ug | Price: €348.2 Supplier: Reliatech antibodies

Gene Name TNF-alpha Species Reactivity Rat (Rattus norvegicus) Synonyms Tnf; Tnfa; RATTNF; TNF-alpha
Anti-mouse gm-csf Catalog: 103-PA06S | Size: 100ug | Price: €216.13 Supplier: Reliatech antibodies

Gene Name GM-CSF Species Reactivity Mouse (Mus musculus) Synonyms Csf2, Csfgm; GM-CSF; Gm-CSf; MGI-IGM
uid :
2147

name :
F2

description :
coagulation factor II, thrombin

chromosome :
11

geneticsource :
genomic

maplocation :
11p11.2

otheraliases :
PT, RPRGL2, THPH1

otherdesignations :
prothrombin|prepro-coagulation factor II|prothrombin B-chain|serine protease|thrombin factor II

nomenclaturesymbol :
F2

nomenclaturename :
coagulation factor II, thrombin

nomenclaturestatus :
Official

geneweight :
143624

chrsort :
11

chrstart :
46719165

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000011.10
chrstart: 46719165
chrstop: 46739507
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000011.10
chrstart: 46719165
chrstop: 46739507
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46739121
chrstop: 46759463
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000011.10
chrstart: 46719191
chrstop: 46739505
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46739148
chrstop: 46759461
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000011.10
chrstart: 46719191
chrstop: 46739505
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46739148
chrstop: 46759461
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46739148
chrstop: 46759461
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018922.1
chrstart: 46666501
chrstop: 46686814
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46888701
chrstop: 46909013
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000011.9
chrstart: 46740742
chrstop: 46761055
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46888701
chrstop: 46909013
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446659
chrstop: 46466972
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000011.8
chrstart: 46697330
chrstop: 46717630
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46888713
chrstop: 46909012
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46446671
chrstop: 46466971