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anti-BMP3B / GDF10 (369-478) Antibody

Anti-bmp3b / gdf10 (369-478) antibody Catalog: AR09217PU-L | Size: 0,5 mg | Price: €1810.5 Supplier: acr

Vial description: Bone morphogenetic protein 3b, Bone-inducing protein, BIP, GDF-10 Category: antigen Raised in: laboratory

BMP3 gene: bone morphogenetic protein 3

BMP-3A

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]

Organism: human (Homo sapiens)