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BMP3 Antibody

Bmp3 antibody Catalog: F45376-0.4ML | Size: 0.4 ml | Price: €490.04 Supplier: NJS poly

Category: Antibody Concentration: In 1X PBS, pH 7.4, with 0.09% sodium azide Form: Purified

BMP3 gene: bone morphogenetic protein 3

BMP-3A

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]

Organism: human (Homo sapiens)