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BMP-3 CRISPR Knockout and Activation Products (m)

bmp-3 crispr knockout and activation products (m)

Catalog: sc-430986 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 BMP-3 CRISPR Knockout and Activation Products (m)  BMP-3 CRISPR Knockout and Activation Products (m)  BMP-3 CRISPR Knockout and Activation Products (m)  BMP-3 CRISPR Knockout and Activation Products (m)

mouse BMP-3-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

BMP3 gene: bone morphogenetic protein 3

BMP-3A

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. [provided by RefSeq, Jul 2016]

Organism: human (Homo sapiens)