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ARHGAP8: Rho GTPase activating protein 8

BPGAP1, PP610

Summary

This gene encodes a member of the RHOGAP family. GAP (GTPase-activating) family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. GAP proteins alternate between an active (GTP-bound) and inactive (GDP-bound) state based on the GTP:GDP ratio in the cell. This family member is a multidomain protein that functions to promote Erk activation and cell motility. Alternative splicing results in multiple transcript variants. Read-through transcripts from the upstream proline rich 5, renal (PRR5) gene into this gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]

Organism: human (Homo sapiens)

ARHGAP8 related publications

The DNA sequence of human chromosome 22.

ARHGAP8 description

Prr5 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV274129 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Prr5 antibody Catalog: GWB-MU499D | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Prr5-arhgap8 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV274135 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Prr5 peptide Catalog: ZP-6291 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

ASK
Alternative name PRR5 short protein sequence Gene target PRR5 Peptide Technique peptide
Prr5 antibody Catalog: GWB-MU498C | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Anti-prr5 control peptide antibody Catalog: AP26126CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

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Vial description Proline-rich protein 5ROTOR1rotor-1 Category control peptide Raised in laboratory
Anti-prr5 antibody Catalog: 6291 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

ASK
Gene info PRR5 Antibody: Proline-rich protein 5 (PRR5), also known as Protor-1, is a 388 amino acid protein in Protor family, is thought to act as a tumor suppressor in breast and colorectal tumorigenesis. PRR5 is widely expressed and possesses two RICTOR interaction sites and a C-terminal Proline rich region. It promotes Rapamycin complex 2 (mTORC2) activity. There are four isoforms of PRR5 that are produced as a result of alternative splicing events and these isoforms play an important role in the modulation of platelet-derived growth factor signaling and in the regulation of PDGFR-beta expression. Gene names PRR5 Antibody: PP610, PROTOR1, PROTOR-1, FLJ20185k, PP610, Proline-rich protein 5, Protein observed with Rictor-1, Protor-1 Antibodie's label unlabelled serum
Prr5 antibody Catalog: 70R-5245 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Cancer
Prr5 antibody Catalog: 70R-9436 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Neuroscience
Prr5 antibody Catalog: 70R-19558 | Size: 50 µl | Price: €614.76 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Signal Transduction
Prr5 blocking peptide Catalog: 33R-6877 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

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Category Proteins Antibody Subtype Blocking Peptides Area of research Neuroscience
Prr5 blocking peptide Catalog: 33R-3387 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

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Category Proteins Antibody Subtype Blocking Peptides Area of research Cancer
Prr5 antibody - n-terminal region Catalog: ARP56749_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen PRR5 - N-terminal region Product type Antibody Gene name PRR5
Prr5 antibody - c-terminal region Catalog: ARP56750_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen PRR5 - C-terminal region Product type Antibody Gene name PRR5
Arhgap8 antibody - middle region Catalog: ARP65532_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen ARHGAP8 - middle region Product type Antibody Gene name ARHGAP8
Prr5 antibody Catalog: OALA06027 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen PRR5 Product type Antibody Gene name PRR5
Prr5 antibody Catalog: OAPB01285 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen PRR5 Product type Antibody Gene name PRR5
Anti-human prr5 antibody Catalog: MBS244906 | Size: 50ug | Price: €716.82 Supplier: MBS Polyclonals

ASK
Alternative name1 Anti-Rabbit Polyclonal to Human PRR5 Alternative name2 Rabbit PAb to Human PRR5 Alternative name3 Lapin Polyclonal to Homo sapiens PRR5
Prr5 antibody Catalog: MBS150063 | Size: 100ug | Price: €517.5 Supplier: MBS Polyclonals

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Alternative name1 Anti-PRR5 Antibody Alternative name2 PRR5, Anti- Alternative name3 PRR5 Antibody
Human arhgap8 crispr knock out 293t cell line Catalog: K0114951 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293T NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out 293 cell line Catalog: K0114952 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out a549 cell line Catalog: K0114953 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type A549 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out hela cell line Catalog: K0114954 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HeLa NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out mda-mb-435 cell line Catalog: K0114955 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MDA-MB-435 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out hepg2 cell line Catalog: K0114956 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HepG2 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out mcf7 cell line Catalog: K0114957 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MCF7 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out k562 cell line Catalog: K0114958 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type K562 NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human arhgap8 crispr knock out u87-mg cell line Catalog: K0114959 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type U87-MG NCBI number NM_001017526 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out 293t cell line Catalog: K1730151 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293T NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out 293 cell line Catalog: K1730152 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out a549 cell line Catalog: K1730153 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type A549 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out hela cell line Catalog: K1730154 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HeLa NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out mda-mb-435 cell line Catalog: K1730155 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MDA-MB-435 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out hepg2 cell line Catalog: K1730156 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HepG2 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out mcf7 cell line Catalog: K1730157 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MCF7 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out k562 cell line Catalog: K1730158 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type K562 NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5 crispr knock out u87-mg cell line Catalog: K1730159 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type U87-MG NCBI number NM_181333 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5-arhgap8 crispr knock out 293t cell line Catalog: K2795051 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293T NCBI number NM_181334 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5-arhgap8 crispr knock out 293 cell line Catalog: K2795052 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293 NCBI number NM_181334 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human prr5-arhgap8 crispr knock out a549 cell line Catalog: K2795053 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type A549 NCBI number NM_181334 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
uid :
23779

name :
ARHGAP8

description :
Rho GTPase activating protein 8

chromosome :
22

geneticsource :
genomic

maplocation :
22q13.31

otheraliases :
BPGAP1, PP610

otherdesignations :
rho GTPase-activating protein 8|BCH domain-containing Cdc42GAP-like protein|BNIP-2 and Cdc42GAP homology domain-containing, proline-rich and Cdc42GAP-like protein subtype-1|rho-type GTPase-activating protein 8

nomenclaturesymbol :
ARHGAP8

nomenclaturename :
Rho GTPase activating protein 8

nomenclaturestatus :
Official

geneweight :
2282

chrsort :
22

chrstart :
44752557

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000022.11
chrstart: 44752557
chrstop: 44862783
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000022.11
chrstart: 44752557
chrstop: 44862783
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018933.2
chrstart: 45141076
chrstop: 45217386
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000022.11
chrstart: 44752557
chrstop: 44862783
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018933.2
chrstart: 45141076
chrstop: 45217386
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000022.11
chrstart: 44752557
chrstop: 44862783
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018933.2
chrstart: 45141076
chrstop: 45217386
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018933.2
chrstart: 45141076
chrstop: 45217386
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018933.1
chrstart: 29099237
chrstop: 29175780
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000065.1
chrstart: 29060361
chrstop: 29170595
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000022.10
chrstart: 45148437
chrstop: 45258663
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000065.1
chrstart: 29060361
chrstop: 29170595
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000022.9
chrstart: 43527101
chrstop: 43637327
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000065.1
chrstart: 29060361
chrstop: 29170595
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000154.1
chrstart: 28096687
chrstop: 28205948