This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Other name Rho GTPase-activating protein 42,Rho GTPase-activating protein 10-like,Rho-type GTPase-activating protein 42,ARHGAP42,GRAF31Immunogen Recombinant human Rho GTPase-activating protein 42 protein (541-728AA)Verified reactivity Human
Cell line type 293TNCBI number NG_002375Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
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Cell line type 293NCBI number NM_032021Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_032021Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_032021Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_032021Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
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Cell line type 293NCBI number NM_152432Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_152432Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_152432Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_152432Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
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Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU001080 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
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uid :
143872
name :
ARHGAP42
description :
Rho GTPase activating protein 42
chromosome :
11
geneticsource :
genomic
maplocation :
11q22.1
otheraliases :
AD031, GRAF3, TMEM133
otherdesignations :
rho GTPase-activating protein 42|rho-type GTPase-activating protein 42|transmembrane protein 133