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All about genes

ARHGAP42: Rho GTPase activating protein 42

AD031, GRAF3, TMEM133

Summary

This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]

Organism: human (Homo sapiens)

ARHGAP42 description

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Old catalog number 36-614-466108 Storage temperature store cold Expiry date 1 y
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Other name Rho GTPase-activating protein 42,Rho GTPase-activating protein 10-like,Rho-type GTPase-activating protein 42,ARHGAP42,GRAF31 Immunogen Recombinant human Rho GTPase-activating protein 42 protein (541-728AA) Verified reactivity Human
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uid :
143872

name :
ARHGAP42

description :
Rho GTPase activating protein 42

chromosome :
11

geneticsource :
genomic

maplocation :
11q22.1

otheraliases :
AD031, GRAF3, TMEM133

otherdesignations :
rho GTPase-activating protein 42|rho-type GTPase-activating protein 42|transmembrane protein 133

nomenclaturesymbol :
ARHGAP42

nomenclaturename :
Rho GTPase activating protein 42

nomenclaturestatus :
Official

geneweight :
1199

chrsort :
11

chrstart :
100687239

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000011.10
chrstart: 100687239
chrstop: 100993944
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000011.10
chrstart: 100687675
chrstop: 100993940
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 100441818
chrstop: 100744896
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000011.10
chrstart: 100687675
chrstop: 100990924
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 100441818
chrstop: 100744896
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000011.10
chrstart: 100687675
chrstop: 100990924
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 100441818
chrstop: 100744896
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 100441818
chrstop: 100744896
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018922.1
chrstart: 100428510
chrstop: 100731680
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 97727720
chrstop: 98030994
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000011.9
chrstart: 100558406
chrstop: 100861655
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 97727720
chrstop: 98030994
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494880
chrstop: 96798723
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000011.8
chrstart: 100063619
chrstop: 100354993
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 97727723
chrstop: 98019113
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 96494883
chrstop: 96786836