Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Gene names ARHGAP26, Rho GTPase activating protein 26, GRAF, KIAA0621, FLJ42530, OPHN1L, OPHN1L1, GTPase regulator associated with FAK, GTPase regulator associated with focal adhesion kinase pp125(FAK), GTPase regulator associated with the focal adhesion kinase pp125Antibodie's label unlabelled serumPurity GRAF antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Other name ARHGAP26; GRAF; Rho GTPase activating protein 26 ; KIAA0621; FLJ42530; OPHN1L; OPHN1L1; GTPase regulator associated with FAK; GTPase regulator associated with focal adhesion kinase pp125(FAK); GTPase regulator associated with the focal adhesion kinase pp1Immunogen C-KTGLIPENYVEFLVerified reactivity Human
Alternative name1 Anti-RABBIT ANTI HUMAN FOCAL ADHESION KINASEAlternative name2 RABBIT ANTI HUMAN FOCAL ADHESION KINASEAlternative name3 Lapin ANTI Homo sapiens FOCAL ADHESION KINASE
Cell line type 293TNCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type 293NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HepG2NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MCF7NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type K562NCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type U87-MGNCBI number NM_015071Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU001069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU051069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h01069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h51069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h01069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h51069 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
uid :
23092
name :
ARHGAP26
description :
Rho GTPase activating protein 26
chromosome :
5
geneticsource :
genomic
maplocation :
5q31.3
otheraliases :
GRAF, GRAF1, OPHN1L, OPHN1L1
otherdesignations :
rho GTPase-activating protein 26|GTPase regulator associated with focal adhesion kinase pp125(FAK)|oligophrenin-1-like protein