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APPL1: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

APPL, DIP13alpha, MODY14

Summary

The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)

APPL1 description

Appl1 over-expression lysate reagent Catalog: GWB-396F43 | Size: 1 x 1 vial | Price: €674.79 Supplier: genways

ASK
Old catalog number 36-614-462693 Storage temperature store cold Expiry date 1 y
Appl1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV078320 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Appl1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV078324 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Appl1 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV078323 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Appl1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV078319 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Appl1 antibody Catalog: GWB-MT571D | Size: 1 vial | Price: €625.56 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Appl1 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV078321 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Anti-appl1 antibody Catalog: A02A0239 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

ASK
The antibodie's description anti-Adaptor protein APPL; Adaptor protein containing pH domain, PTB domain and leucine zipper motif; DIP13 alpha; DP13A; KIAA1428; Signaling adaptor protein DIP13alpha antibody The antigen used epitope of the human, mouse Adaptor protein APPL; Adaptor protein containing pH domain, PTB domain and leucine zipper motif; DIP13 alpha; DP13A; KIAA1428; Signaling adaptor protein DIP13alpha antigen Gene name Adaptor protein APPL; Adaptor protein containing pH domain, PTB domain and leucine zipper motif; DIP13 alpha; DP13A; KIAA1428; Signaling adaptor protein DIP13alpha
Appl1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV078322 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Appl1 antibody Catalog: R30460 | Size: 0.1mg | Price: €467.07 Supplier: NJS poly

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Category Antibody Concentration 0.5mg/ml if reconstituted with 0.2ml sterile DI water Form Antigen affinity purified
Appl antibody Catalog: R33528-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

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Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Appl1 antibody Catalog: R34912-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

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Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Anti-appl1 / dip13a (c-term) antibody Catalog: AP32796PU-N | Size: 0,1 mg | Price: €669.99 Supplier: acr

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Vial description Dip13-alpha, KIAA1428 Category primary antibody Raised in Goat
Anti-appl1 / dip13a antibody Catalog: BB-PA1389 | Size: 0,1 mg | Price: €565.53 Supplier: acr

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Vial description Dip13-alpha, KIAA1428 Category primary antibody Raised in Rabbit
Eph/ief sample appl foil 24s ( Catalog: 83-251 | Size: 5/Unit | Price: €249.75 Supplier: Genesee

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Description GE# 80-1129-47 Alternative name EPH/IEF SAMPLE APPL FOIL 24S ( Gene target EPH/IEF APPL FOIL 24S
Ief sample appl pieces (pkg/20 Catalog: 83-270 | Size: 200/Unit | Price: €242.54 Supplier: Genesee

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Description GE# 80-1129-46 Alternative name IEF SAMPLE APPL PIECES (PKG/20 Gene target IEF APPL PIECES (PKG/20
Ief/sds sample appl strip 52s( Catalog: 83-271 | Size: 5/Unit | Price: €421.45 Supplier: Genesee

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Description GE# 18-1002-26 Alternative name IEF/SDS SAMPLE APPL STRIP 52S( Gene target IEF/SDS APPL 52S(
Imm sample appl strip 52s (pkg Catalog: 83-272 | Size: 5/Unit | Price: €386.63 Supplier: Genesee

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Description GE# 18-1002-76 Alternative name IMM SAMPLE APPL STRIP 52S (PKG Gene target IMM APPL 52S (PKG
Sds sample appl strip 26s (pkg Catalog: 83-289 | Size: 5/Unit | Price: €441.86 Supplier: Genesee

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Description GE# 18-1002-74 Alternative name SDS SAMPLE APPL STRIP 26S (PKG Gene target SDS APPL 26S (PKG
Phastgel sample appl. 8/0.5 Catalog: 83-706 | Size: 50/Unit | Price: €298.97 Supplier: Genesee

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Description GE# 18-1617-01 Alternative name PHASTGEL SAMPLE APPL. 8/0.5 Gene target PHASTGEL APPL. 8/0.5
Phastgel sample appl. 8/1 Catalog: 83-707 | Size: 50/Unit | Price: €306.18 Supplier: Genesee

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Description GE# 18-1618-01 Alternative name PHASTGEL SAMPLE APPL. 8/1 Gene target PHASTGEL APPL. 8/1
Phastgel sample appl.12/0.3 Catalog: 83-708 | Size: 50/Unit | Price: €298.97 Supplier: Genesee

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Description GE# 18-1614-01 Alternative name PHASTGEL SAMPLE <a href="http://APPL.12/0.3" target="_blank" title="APPL.12/0.3"><i class="fa fa-external-link" aria-hidden="true"></i></a> Gene target PHASTGEL <a href="http://APPL.12/0.3" target="_blank" title="APPL.12/0.3"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Anti-appl1 antibody Catalog: 45-271 | Size: 0.1 mg | Price: €216.13 Supplier: proscience

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Gene names APPL1, DIP13alpha, adaptor protein containing pH domain, PTB domain and leucine zipper motif, signaling adaptor protein DIP13alpha, APPL, DIP13A, KIAA1428 Antibodie's label unlabelled serum Purity APPL1 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Appl1 antibody Catalog: 70R-2700 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Cell Biology
Appl1 antibody Catalog: 70R-13931 | Size: 100 µg | Price: €459.87 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Cell Biology
Appl1 antibody Catalog: 70R-15782 | Size: 50 µl | Price: €614.76 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Signal Transduction
Appl1 antibody Catalog: 70R-35834 | Size: 100 µg | Price: €467.07 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research DNA & RNA
Appl1 antibody Catalog: 70R-36711 | Size: 100 µg | Price: €497.09 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Differentiation & Development
Appl1 blocking peptide Catalog: 33R-3487 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

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Category Proteins Antibody Subtype Blocking Peptides Area of research Cell Biology
Appl1 recombinant protein Catalog: OPCD01456 | Size: one vial | Price: €278.56 Supplier: aviva

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Storage For short term storage APPL1 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius. Tips Due to handling and transportation, small amounts of the APPL1 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance. Alternative name APPL1 recombinant Protein
Appl1 antibody - middle region Catalog: ARP54834_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen APPL1 - middle region Product type Antibody Gene name APPL1
Appl1 antibody - middle region Catalog: ARP81032_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen APPL1 - middle region Product type Antibody Gene name APPL1
Appl1 antibody Catalog: OAAF03557 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 Product type Antibody Gene name APPL1
Appl1 antibody Catalog: OAAF06106 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 Product type Antibody Gene name APPL1
Appl1 polyclonal antibody Catalog: OABB00347 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 Polyclonal Product type Antibody Gene name APPL1 Polyclonal
Appl1 antibody Catalog: OAEB02115 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 Product type Antibody Gene name APPL1
Goat anti-appl / dip13alpha -c-terminal region antibody Catalog: OAEB02610 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen Goat APPL / DIP13alpha -C-terminal region Product type Antibody Gene name Goat APPL / DIP13alpha -C-terminal region
Appl1 antibody Catalog: OALA08486 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 Product type Antibody Gene name APPL1
Appl1 antibody - middle region Catalog: OASG00477 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen APPL1 - middle region Product type Antibody Gene name APPL1
Adaptor protein phosphotyrosine interaction ph domain and leucine zipper containing protein 1 (appl1) polyclonal antibody Catalog: CAU21504 | Size: 10 μg | Price: €219.73 Supplier: bioma

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Other name APPL; DIP13A; DIP13alpha; DCC-interacting protein 13-alpha Immunogen APPL1 (Phe404~Ser673) Verified reactivity Homo sapiens (Human)
uid :
26060

name :
APPL1

description :
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

chromosome :
3

geneticsource :
genomic

maplocation :
3p14.3

otheraliases :
APPL, DIP13alpha, MODY14

otherdesignations :
DCC-interacting protein 13-alpha|AKT2 interactor|adapter protein containing PH domain, PTB domain and leucine zipper motif 1|adaptor protein containing pH domain, PTB domain and leucine zipper motif 1|adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1|dip13-alpha|signaling adaptor protein DIP13alpha

nomenclaturesymbol :
APPL1

nomenclaturename :
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

nomenclaturestatus :
Official

geneweight :
6908

chrsort :
03

chrstart :
57227736

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000003.12
chrstart: 57227736
chrstop: 57273470
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000003.12
chrstart: 57227736
chrstop: 57273470
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018914.2
chrstart: 57211912
chrstop: 57257645
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000003.12
chrstart: 57227736
chrstop: 57273470
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018914.2
chrstart: 57211912
chrstop: 57257645
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000003.12
chrstart: 57227736
chrstop: 57273470
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018914.2
chrstart: 57211912
chrstop: 57257645
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018914.2
chrstart: 57211912
chrstop: 57257645
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018914.1
chrstart: 57195479
chrstop: 57241212
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000046.1
chrstart: 57227339
chrstop: 57273072
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000003.11
chrstart: 57261764
chrstop: 57307498
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000046.1
chrstart: 57227339
chrstop: 57273072
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000003.10
chrstart: 57236804
chrstop: 57282538
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000046.1
chrstart: 57227339
chrstop: 57273072
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000135.1
chrstart: 57310966
chrstop: 57356663