This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
Alternative name 1 Kappa (free), Clone: 2B7, Mab anti-Human, frozen/paraffinAlternative name 2 Kappa (free), Clone: 2B7, Mab antibody-Human, frozen/paraffinAlternative name 3 Kappa (free), Clone: 2B7, Mab antibody-Homo sapiens, frozen/paraffin
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 Rat Kappa 1b allotype, Clone: LORK1b-2, Rat Mab anti-, BiotinAlternative name 2 Rat Kappa 1b allotype, Clone: LORK1b-2, Rat Mab antibody-, BiotinAlternative name 3 Rattus norvegicus Kappa 1b allotype, Clone: LORK1b-2, Rattus norvegicus Mab antibody-, Biotin
Alternative name 1 NF Kappa B Inhibitor Beta, Mab anti-; Clone: 1B5Alternative name 2 NF Kappa B Inhibitor Beta, Mab antibody-; Clone: 1B5Alternative name 3 NF Kappa B Inhibitor Beta, Mab antibody-; Clone: 1B5
Alternative name 1 Rat Kappa 1a allotype (weak x w/ Rat IgK1b), Clone: MARK-3, Mab anti-Alternative name 2 Rat Kappa 1a allotype (weak x w/ Rat IgK1b), Clone: MARK-3, Mab antibody-Alternative name 3 Rattus norvegicus Kappa 1a allotype (weak x w/ Rattus norvegicus IgK1b), Clone: MARK-3, Mab antibody-
Alternative name 1 Rat IgA Kappa, Clone: IR22, MyelomaAlternative name 2 Rat IgA Kappa, Clone: IR22, MyelomaAlternative name 3 Rattus norvegicus IgA Kappa, Clone: IR22, Myeloma
Alternative name 1 Mouse Kappa (min X Ch,Rb,Gt,Sh,Hr,Bab,Hu IgG, Hu IgM), Clone: LOMK2, Rat Mab anti-, BiotinAlternative name 2 Mouse Kappa (min X Ch,Rb,Gt,Sh,Hr,Bab,Hu IgG, Hu IgM), Clone: LOMK2, Rat Mab antibody-, BiotinAlternative name 3 Mus musculus Kappa (min X Ch,Rb,Gt,Sh,Hr,Bab,Hu IgG, Hu IgM), Clone: LOMK2, Rattus norvegicus Mab antibody-, Biotin
Alternative name 1 CD41/61 (platelets), Clone: CAPP2A, Mab anti-Bovine,Goat,SheepAlternative name 2 CD41/61 (platelets), Clone: CAPP2A, Mab antibody-Bovine,Goat,SheepAlternative name 3 CD41/61 (platelets), Clone: CAPP2A, Mab antibody-Bovine,Goat,Ovine
Alternative name 1 Kappa (min X Bov,Gt,Sh,Hrs,Sw,Dog,Rab,GP,Ch,Bab,Ms Ig's), Clone: LO-HK-3, Rat Mab anti-HumanAlternative name 2 Kappa (min X Bov,Gt,Sh,Hrs,Sw,Dog,Rab,GP,Ch,Bab,Ms Ig's), Clone: LO-HK-3, Rat Mab antibody-HumanAlternative name 3 Kappa (min X Bov,Gt,Sh,Hrs,Sw,Canine,Rab,GP,Ch,Bab,Ms Ig's), Clone: LO-HK-3, Rattus norvegicus Mab antibody-Homo sapiens