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Apolipoprotein A-I (APOA1) Goat antibody to or anti-Human Polyclonal antibody

Apolipoprotein a-i (apoa1) goat antibody to or anti-human polyclonal antibody Catalog: GWB-71197B | Size: 1 tube | Price: €722.82 Supplier: genways ASK
Old catalog number: 18-464-435057 Storage temperature: store cold Expiry date: 1 y

APOA1 gene: apolipoprotein A1

apo(a)

Summary

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Organism: human (Homo sapiens)