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Apolipoprotein A1

Apolipoprotein a1 Catalog: SC04B225 | Size: R1:90ml×2 R2:45ml×1 | Price: €113.23 Supplier: Szybio Lambert ASK
Volume of reagent in a kit: 225ml Test field of this automate: Blood Lipid Reagents Insruments of IVD used for this reagent: for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.

APOA1 gene: apolipoprotein A1

apo(a)

Summary

This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]

Organism: human (Homo sapiens)