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AP2S1: adaptor related protein complex 2 subunit sigma 1

AP17, CLAPS2, FBH3, FBHOk, HHC3

Summary

One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Organism: human (Homo sapiens)

AP2S1 related publications

Human CLAPS2 encoding AP17, a small chain of the clathrin-associated protein complex: cDNA cloning and chromosomal assignment to 19q13.2-->q13.3.

A novel spliced transcript of human CLAPS2 encoding a protein alternative to clathrin adaptor protein AP17.

Mutations in AP2S1 cause familial hypocalciuric hypercalcemia type 3.

AP2S1 description

Ap2s1, mouse monoclonal antibody-; clone: 3e4 Catalog: YSRTMCA5228Z | Size: Ask | Price: Ask Supplier: accurate-monoclonals

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Alternative name 1 AP2S1, Mab anti-; Clone: 3E4 Alternative name 2 AP2S1, Mab antibody-; Clone: 3E4 Alternative name 3 AP2S1, Mab antibody-; Clone: 3E4
Ap2s1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV077089 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV077093 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 over-expression lysate reagent Catalog: GWB-CEBB71 | Size: 1 vial | Price: €555.92 Supplier: genways

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Old catalog number 36-614-466749 Storage temperature store cold Expiry date 1 y
Ap2s1 over-expression lysate reagent Catalog: GWB-98414F | Size: 1 vial | Price: €555.92 Supplier: genways

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Old catalog number 36-614-469309 Storage temperature store cold Expiry date 1 y
Ap2s1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV077094 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV077091 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV077090 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV077092 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ap2s1 antibody Catalog: 70R-15355 | Size: 100 µg | Price: €467.07 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Cell Biology
Ap2s1 antibody biotin Catalog: 60R-1879 | Size: 100 µg | Price: €467.07 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Conjugated Polyclonal Antibodies Area of research Cell Biology
Ap2s1 antibody fitc Catalog: 60R-1878 | Size: 100 µg | Price: €467.07 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Conjugated Polyclonal Antibodies Area of research Cell Biology
Ap2s1 antibody hrp Catalog: 60R-1877 | Size: 100 µg | Price: €467.07 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Conjugated Polyclonal Antibodies Area of research Cell Biology
Guinea pig ap-2 complex subunit sigma(ap2s1) elisa kit Catalog: E05A1566 | Size: 96 well immunosorbent assay kit (48 available) | Price: €866.91 Supplier: BlueGen ELISAs

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The ELISA's description AP2S1 ELISA for signal Transduction research Scientific field AP2S1 ELISA for signal Transduction research Type of ELISA competitive ELISA
Ap2s1 antibody - middle region Catalog: OAAB12859 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AP2S1 - middle region Product type Antibody Gene name AP2S1
Ap2s1 antibody Catalog: OACA00965 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AP2S1 Product type Antibody Gene name AP2S1
Ap2s1 antibody - hrp conjugated Catalog: OACA00966 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AP2S1 Product type Antibody Gene name AP2S1
Ap2s1 antibody - biotin conjugated Catalog: OACA00967 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AP2S1 Product type Antibody Gene name AP2S1
Ap2s1 antibody Catalog: A51809-050 | Size: 0.05mg | Price: €362.61 Supplier: Epigen

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Product category Antibodies Conjugation Unconjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51809-100 | Size: 0.1mg | Price: €483.88 Supplier: Epigen

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Product category Antibodies Conjugation Unconjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51810-050 | Size: 0.05mg | Price: €362.61 Supplier: Epigen

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Product category Antibodies Conjugation HRP Conjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51810-100 | Size: 0.1mg | Price: €483.88 Supplier: Epigen

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Product category Antibodies Conjugation HRP Conjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51811-050 | Size: 0.05mg | Price: €362.61 Supplier: Epigen

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Product category Antibodies Conjugation FITC Conjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51811-100 | Size: 0.1mg | Price: €483.88 Supplier: Epigen

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Product category Antibodies Conjugation FITC Conjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51812-050 | Size: 0.05mg | Price: €362.61 Supplier: Epigen

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Product category Antibodies Conjugation Biotin Conjugated Clonality Polyclonal antibody
Ap2s1 antibody Catalog: A51812-100 | Size: 0.1mg | Price: €483.88 Supplier: Epigen

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Product category Antibodies Conjugation Biotin Conjugated Clonality Polyclonal antibody
Ap2s1, id (ap2s1, ap17, claps2, ap-2 complex subunit sigma, adapter-related protein complex 2 sigma subunit, adaptor protein complex ap-2 subunit sigma, clathrin assembly protein 2 small chain, clathr Catalog: MBS647362 | Size: 200ul | Price: €724.02 Supplier: MBS Polyclonals

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Alternative name1 Anti-AP2S1, ID (AP2S1, AP17, CLAPS2, AP-2 complex subunit sigma, Adapter-related protein complex 2 sigma subunit, Adaptor protein complex AP-2 subunit sigma, Clathrin assembly protein 2 small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated Alternative name2 AP2S1, ID (AP2S1, AP17, CLAPS2, AP-2 complex subunit sigma, Adapter-related protein complex 2 sigma subunit, Adaptor protein complex AP-2 subunit sigma, Clathrin assembly protein 2 small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated Alternative name3 AP2S1, ID (AP2S1, AP17, CLAPS2, AP-2 complex subunit sigma, Adapter-related protein complex 2 sigma subunit, Adaptor protein complex AP-2 subunit sigma, Clathrin assembly protein 2 small chain, Clathrin coat assembly protein AP17, Clathrin coat-associated
Human ap2s1 crispr knock out 293t cell line Catalog: K0100851 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293T NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out 293 cell line Catalog: K0100852 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out a549 cell line Catalog: K0100853 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type A549 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out hela cell line Catalog: K0100854 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HeLa NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out mda-mb-435 cell line Catalog: K0100855 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MDA-MB-435 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out hepg2 cell line Catalog: K0100856 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HepG2 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out mcf7 cell line Catalog: K0100857 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MCF7 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out k562 cell line Catalog: K0100858 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type K562 NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human ap2s1 crispr knock out u87-mg cell line Catalog: K0100859 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type U87-MG NCBI number NM_004069 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
uid :
1175

name :
AP2S1

description :
adaptor related protein complex 2 subunit sigma 1

chromosome :
19

geneticsource :
genomic

maplocation :
19q13.32

otheraliases :
AP17, CLAPS2, FBH3, FBHOk, HHC3

otherdesignations :
AP-2 complex subunit sigma|HA2 17 kDa subunit|adaptor protein complex AP-2 subunit sigma|adaptor related protein complex 2 sigma 1 subunit|clathrin assembly protein 2 sigma small chain|clathrin coat assembly protein AP17|clathrin coat-associated protein AP17|clathrin-associated/assembly/adaptor protein, small 2 (17kD)|plasma membrane adaptor AP-2 17 kDa protein|sigma2-adaptin

nomenclaturesymbol :
AP2S1

nomenclaturename :
adaptor related protein complex 2 subunit sigma 1

nomenclaturestatus :
Official

geneweight :
3935

chrsort :
19

chrstart :
46838157

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000019.10
chrstart: 46850994
chrstop: 46838157
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000019.10
chrstart: 46850994
chrstop: 46838157
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 47356146
chrstop: 47343317
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000019.10
chrstart: 46850994
chrstop: 46838157
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 47356146
chrstop: 47343317
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000019.10
chrstart: 46850945
chrstop: 46838165
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 47356097
chrstop: 47343325
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 47356097
chrstop: 47343325
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018930.1
chrstart: 47540014
chrstop: 47527240
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 44158457
chrstop: 44145678
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000019.9
chrstart: 47354202
chrstop: 47341422
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 44158457
chrstop: 44145678
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000019.8
chrstart: 52046042
chrstop: 52033262
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 44158457
chrstop: 44145678
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 43779261
chrstop: 43766566