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All about genes

AMBRA1: autophagy and beclin 1 regulator 1

DCAF3, WDR94

Summary

Organism: human (Homo sapiens)

AMBRA1 related publications

A novel role for autophagy in neurodevelopment.

Autophagy: a new regulator of development.

Ambra1 regulates autophagy and development of the nervous system.

AMBRA1 description

Ambra1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV073630 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 over-expression lysate reagent Catalog: GWB-1E5A03 | Size: 1 x 1 vial | Price: €674.79 Supplier: genways

ASK
Old catalog number 36-614-467348 Storage temperature store cold Expiry date 1 y
Ambra1 antibody, alexa fluor 594 Catalog: bs-3830R-A594 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AMBRA1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated Also known as Anti-AMBRA1 PAb ALEXA FLUOR 594 Category Conjugated Primary Antibodies
Ambra1 antibody (n-terminus) Catalog: GWB-940839 | Size: 1 vial | Price: €404.64 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Ambra1 antibody, alexa fluor 488 Catalog: bs-3830R-A488 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AMBRA1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated Also known as Anti-AMBRA1 PAb ALEXA FLUOR 488 Category Conjugated Primary Antibodies
Ambra1 antibody Catalog: AUT-4557 | Size: 0.1 mg | Price: €589.54 Supplier: Zyagen

ASK
Alternative name Ambra1 (Antibody to) Gene target Ambra1 Short name Ambra1 Antibody
Ambra1 antibody, alexa fluor 647 Catalog: bs-3830R-A647 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AMBRA1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated Also known as Anti-AMBRA1 PAb ALEXA FLUOR 647 Category Conjugated Primary Antibodies
Ambra1 antibody (c-terminus) Catalog: GWB-565B4A | Size: 1 x 1 vial | Price: €404.64 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Ambra1 antibody Catalog: AUT-4555 | Size: 0.1 mg | Price: €589.54 Supplier: Zyagen

ASK
Alternative name Ambra1 (Antibody to) Gene target Ambra1 Short name Ambra1 Antibody
Ambra1 antibody (n-terminus) Catalog: GWB-E50032 | Size: 1 vial | Price: €814.07 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Ambra1 antibody, alexa fluor 350 Catalog: bs-3830R-A350 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AMBRA1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated Also known as Anti-AMBRA1 PAb ALEXA FLUOR 350 Category Conjugated Primary Antibodies
Ambra1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV073627 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 peptide Catalog: ZP-4555 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

ASK
Alternative name Ambra1 short protein sequence Gene target Ambra1 Peptide Technique peptide
Ambra1 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV073629 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV073631 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 antibody (c-terminus) Catalog: GWB-D033DD | Size: 1 vial | Price: €841.69 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Ambra1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV073628 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 antibody Catalog: bs-3830R | Size: 0.1ml | Price: €315.78 Supplier: Bioss Primary Unconjugated Antibodies

ASK
Long name AMBRA1 Primary Polyclonal Antibody Also known as AMBRA1 PAb Category Primary Antibodies
Ambra1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV073632 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Ambra1 antibody, alexa fluor 555 Catalog: bs-3830R-A555 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AMBRA1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated Also known as Anti-AMBRA1 PAb ALEXA FLUOR 555 Category Conjugated Primary Antibodies
Ambra1 peptide Catalog: ZP-4557 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

ASK
Alternative name Ambra1 short protein sequence Gene target Ambra1 Peptide Technique peptide
Anti-ambra1 (c-term) antibody Catalog: AP22676PU-N | Size: 50 Вµg | Price: €878.91 Supplier: acr

ASK
Vial description KIAA1736 Category primary antibody Raised in Rabbit
Anti-ambra1 control peptide antibody Catalog: AP30047CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

ASK
Vial description KIAA1736 Category control peptide Raised in laboratory
Anti-ambra1 control peptide antibody Catalog: AP30048CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

ASK
Vial description KIAA1736 Category control peptide Raised in laboratory
Anti-ambra1 antibody Catalog: AP54764SU-N | Size: 0,2 ml | Price: €756.44 Supplier: acr

ASK
Vial description KIAA1736 Category primary antibody Raised in Rabbit
Anti-ambra1 antibody Catalog: 4555 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

ASK
Gene info Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist. Gene names Ambra1 Antibody: DCAF3, WDR94, KIAA1736, Activating molecule in BECN1-regulated autophagy protein 1 Antibodie's label unlabelled serum
Anti-ambra1 antibody Catalog: 4557 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

ASK
Gene info Ambra1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. Beclin-1, a principal regulator of autophagosome formation, is in turn regulated by Ambra1. Ambra1 associates with Beclin-1 through a region near its center as determined by yeast two-hybrid assay. Null mutations in this gene in mice resulted in embryonic lethality with severe neural tube defects associated with autophagy impairment, accumulation of ubiquitinated proteins, unbalanced cell proliferation and excessive apoptotic death. Furthermore, down-regulation of Ambra1 in cultured cells though RNA interference decreased the level of rapamycin- and nutrient starvation-induced autophagy. Multiple isoforms of Ambra1 are known to exist. Gene names Ambra1 Antibody: DCAF3, WDR94, KIAA1736, Activating molecule in BECN1-regulated autophagy protein 1 Antibodie's label unlabelled serum
Ambra1 antibody Catalog: 70R-15693 | Size: 50 µl | Price: €614.76 Supplier: fitzgerald

ASK
Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Differentiation & Development
Guinea pig activating molecule in becn1-regulated autophagy protein 1(ambra1) elisa kit Catalog: E05A1416 | Size: 96 well immunosorbent assay kit (48 available) | Price: €866.91 Supplier: BlueGen ELISAs

ASK
The ELISA's description AMBRA1 ELISA for Neurobiology research Scientific field AMBRA1 ELISA for Neurobiology research Domain Neurobiology
Ambra1 antibody - n-terminal region Catalog: OAAB13791 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AMBRA1 - N-terminal region Product type Antibody Gene name AMBRA1
Ambra1 antibody Catalog: OAAN00203 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AMBRA1 Product type Antibody Gene name AMBRA1
Ambra1 antibody Catalog: OABF01333 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AMBRA1 Product type Antibody Gene name AMBRA1
Ambra1 antibody Catalog: OALA03166 | Size: one vial | Price: €509.1 Supplier: aviva

ASK
Recognized antigen AMBRA1 Product type Antibody Gene name AMBRA1
Ambra1 antibody Catalog: OALA06642 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen AMBRA1 Product type Antibody Gene name AMBRA1
Ambra1 antibody Catalog: OAPB00662 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen Ambra1 Product type Antibody Gene name Ambra1
Ambra1 antibody Catalog: OAPB00663 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen Ambra1 Product type Antibody Gene name Ambra1
Ambra1 antibody - c-terminal region Catalog: OASA06967 | Size: one vial | Price: €509.1 Supplier: aviva

ASK
Recognized antigen AMBRA1 - C-terminal region Product type Antibody Gene name AMBRA1
uid :
55626

name :
AMBRA1

description :
autophagy and beclin 1 regulator 1

chromosome :
11

geneticsource :
genomic

maplocation :
11p11.2

otheraliases :
DCAF3, WDR94

otherdesignations :
activating molecule in BECN1-regulated autophagy protein 1|DDB1 and CUL4 associated factor 3|WD repeat domain 94|activating molecule in beclin-1-regulated autophagy|autophagy/beclin-1 regulator 1

nomenclaturesymbol :
AMBRA1

nomenclaturename :
autophagy and beclin 1 regulator 1

nomenclaturestatus :
Official

geneweight :
3556

chrsort :
11

chrstart :
46396411

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000011.10
chrstart: 46594068
chrstop: 46396411
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000011.10
chrstart: 46594068
chrstop: 46396411
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46614030
chrstop: 46416413
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000011.10
chrstart: 46594068
chrstop: 46396411
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46614030
chrstop: 46416413
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000011.10
chrstart: 46594068
chrstop: 46396411
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46322306
chrstop: 46124696
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46614030
chrstop: 46416413
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000011.9
chrstart: 46615618
chrstop: 46417961
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46322306
chrstop: 46124696
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 46614030
chrstop: 46416413
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000011.9
chrstart: 46615618
chrstop: 46417961
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46322306
chrstop: 46124696
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018922.1
chrstart: 46541396
chrstop: 46343588
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000011.9
chrstart: 46615618
chrstop: 46417961
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46322306
chrstop: 46124696
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000011.9
chrstart: 46612913
chrstop: 46417963
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46319405
chrstop: 46124698
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000011.9
chrstart: 46612913
chrstop: 46417963
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46760893
chrstop: 46566034
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46319405
chrstop: 46124698
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000011.9
chrstart: 46612913
chrstop: 46417963
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46760893
chrstop: 46566034
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46319405
chrstop: 46124698
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000011.8
chrstart: 46569489
chrstop: 46374540
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 46760893
chrstop: 46566035
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 46319405
chrstop: 46124699