The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Available sizes 50ug:198,100ug:330Store store in freezer for long therm or fridge for short time storageCategory research antibodies, ELISAs, e. Coli rec. human proteins
Long name Islet-1+2 Polyclonal Antibody, ALEXA FLUOR 350 ConjugatedAlso known as Anti-Islet-1+2 PAb ALEXA FLUOR 350Category Conjugated Primary Antibodies
Available sizes 50ug:66,100ug:171,1000ug:1870Store store in freezer for long therm or fridge for short time storageCategory research antibodies, ELISAs, e. Coli rec. human proteins
Alternative name 1 CD59, MAC Inhibitor, Leukocyte, Platelet, RBC's, Clone: MEM-43/5, Mab anti-HumanAlternative name 2 CD59, MAC Inhibitor, Leukocyte, Platelet, RBC's, Clone: MEM-43/5, Mab antibody-HumanAlternative name 3 CD59, MAC Inhibitor, Leukocyte, Platelet, RBC's, Clone: MEM-43/5, Mab antibody-Homo sapiens
Alternative name 1 CD59, MAC Inhibitor, Hematopoietic/non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab anti-Human, RPE; flowAlternative name 2 CD59, MAC Inhibitor, Hematopoietic/non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab antibody-Human, RPE; flowAlternative name 3 CD59, MAC Inhibitor, Hematopoietic/non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab antibody-Homo sapiens, RPE; flow
Long name ALS2/Alsin Polyclonal Antibody, ALEXA FLUOR 488 ConjugatedAlso known as Anti-ALS2/Alsin PAb ALEXA FLUOR 488Category Conjugated Primary Antibodies
Long name ALS2CR1/NIF3L1 Polyclonal Antibody, ALEXA FLUOR 594 ConjugatedAlso known as Anti-ALS2CR1/N3L1 PAb ALEXA FLUOR 594Category Conjugated Primary Antibodies
Long name Galectin-3 Polyclonal Antibody, ALEXA FLUOR 555 ConjugatedAlso known as Anti-Galectin-3 PAb ALEXA FLUOR 555Category Conjugated Primary Antibodies
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 Histiocyte, Myeloid antigen, Clone: MAC 387, Mab anti-HumanAlternative name 2 Histiocyte, Myeloid antigen, Clone: MAC 387, Mab antibody-HumanAlternative name 3 Histiocyte, Myeloid antigen, Clone: MAC 387, Mab antibody-Homo sapiens
Long name Islet-1+2 Polyclonal Antibody, ALEXA FLUOR 488 ConjugatedAlso known as Anti-Islet-1+2 PAb ALEXA FLUOR 488Category Conjugated Primary Antibodies
Available sizes 5ug:83,25ug:182,1000ug:3553Store store in freezer for long therm or fridge for short time storageCategory research antibodies, ELISAs, e. Coli rec. human proteins
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>