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All about genes

ALPP: alkaline phosphatase, placental

ALP, PALP, PLAP, PLAP-1

Summary

The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]

Organism: human (Homo sapiens)

ALPP related publications

Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA.

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

ALPP description

Alkaline phosphatase placental (alpp) mouse antibody to or anti-human monoclonal (h7e8) antibody Catalog: GWB-84102F | Size: 1 vial | Price: €722.82 Supplier: genways

ASK
Old catalog number 20-464-437043 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21A675 | Size: R1：60ml×9 R2：45ml×3 | Price: €141.8 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 675ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase antibody Catalog: GWB-4EC464 | Size: 1 x 1 vial | Price: €682 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Alkaline phosphatase Catalog: SC21H200 | Size: R1：40ml×4 R2：40ml×1 | Price: €100.62 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 200ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase antibody Catalog: GWB-7C9507 | Size: 1 tube | Price: €1165.88 Supplier: genways

ASK
Old catalog number 18-511-244505 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase, placental (alpp) rabbit antibody to or anti-human polyclonal antibody Catalog: GWB-9B0764 | Size: 1 vial | Price: €778.05 Supplier: genways

ASK
Old catalog number 18-464-435154 Storage temperature store cold Expiry date 1 y
Alppl2 mouse monoclonal antibody (m07), clone 2b3 Catalog: APO-000251-M07 | Size: 0.1mg | Price: €594.35 Supplier: Zyagen

ASK
Alternative name ALPPL2 Mouse monoclonal (Antibody to) (M07), clonality 2B3 Gene target ALPPL2 Monoclonal (M07) 2B3 Host mouse monoclonal
Alkaline phosphatase Catalog: SC21H250 | Size: R1：50ml×4 R2：50ml×1 | Price: €92.38 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 250ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase antibody Catalog: GWB-8A4C93 | Size: 1 vial | Price: €682 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Alkaline phosphatase Catalog: SC21A225 | Size: R1：60ml×3 R2：45ml×1 | Price: €130.46 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 225ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Kiaa1704 antibody Catalog: GWB-MU755H | Size: 1 vial | Price: €625.56 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Alpp antibody Catalog: GWB-11F423 | Size: 1 x 1 vial | Price: €493.49 Supplier: genways

ASK
Old catalog number 18-003-43718 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21N200 | Size: R1 40ml×4 R2 40ml×1 | Price: €107.68 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 200ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Antibody to or anti- alkaline phosphatase bovine antibody Catalog: GWB-174B57 | Size: 1 x 1 vial | Price: €916.13 Supplier: genways

ASK
Old catalog number 18-251-404850 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21D150 | Size: R1：60ml×2 R2：30ml×1 | Price: €106.5 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 150ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase Catalog: SC21A150 | Size: R1：60ml×2 R2：30ml×1 | Price: €118.27 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 150ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase Catalog: GWB-F2F180 | Size: 1 vial | Price: €959.36 Supplier: genways

ASK
Old catalog number 11-783-79474 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21A450 | Size: R1：60ml×6 R2：45ml×2 | Price: €115.33 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 450ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Kiaa1704 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV199016 | Size: 1.0 µg DNA | Price: €621.36 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alppl2 antibody Catalog: GWB-C9DDF0 | Size: 1 vial | Price: €493.49 Supplier: genways

ASK
Old catalog number 18-003-44298 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21A075 | Size: R1：60ml×1 R2：15ml×1 | Price: €112.39 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 75ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Placental alkaline phosphatase antibody Catalog: GWB-5B15F7 | Size: 1 x 1 vial | Price: €555.92 Supplier: genways

ASK
Old catalog number 18-272-198234 Storage temperature store cold Expiry date 1 y
Alpp over-expression lysate reagent Catalog: GWB-8AEB9C | Size: 1 vial | Price: €555.92 Supplier: genways

ASK
Old catalog number 36-614-470085 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase human, antibody Catalog: GWB-243CDB | Size: 1 x 1 vial | Price: €638.77 Supplier: genways

ASK
Old catalog number 20-251-401259 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase bovine Catalog: GWB-F3870A | Size: Ask | Price: Ask Supplier: genways bulk

ASK
Available sizes 1mg:83,5mg:270,35mg:1579 Old catalog number 11-663-45877 Store store in freezer for long therm or fridge for short time storage
Alpp (421ct8.1.1) monoclonal antibody Catalog: bsm-51131M | Size: 0.1ml | Price: €253.35 Supplier: Bioss Primary Unconjugated Antibodies

ASK
Long name ALPP (421<a href="http://CT8.1.1)" target="_blank" title="CT8.1.1)"><i class="fa fa-external-link" aria-hidden="true"></i></a> Monoclonal Antibody Also known as ALPP (421<a href="http://CT8.1.1)" target="_blank" title="CT8.1.1)"><i class="fa fa-external-link" aria-hidden="true"></i></a> Monoclonal Antibody Category Primary Antibodies
Antibody to or anti-alkaline phosphatase (goat) antibody Catalog: GWB-3AD827 | Size: 1 x 1 vial | Price: €800.87 Supplier: genways

ASK
Old catalog number 18-732-292025 Storage temperature store cold Expiry date 1 y
Alkaline phosphatase Catalog: SC21B225 | Size: R1：90ml×2 R2：45ml×1 | Price: €115.33 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 225ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase Catalog: GWB-C65909 | Size: 1 vial | Price: €625.56 Supplier: genways

ASK
Old catalog number 18-251-404700 Storage temperature store cold Expiry date 1 y
Placental alkaline phosphatase antibody Catalog: GWB-154E9E | Size: 1 x 1 vial | Price: €1035 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Alkaline phosphatase Catalog: SC21A030 | Size: R1：24ml×1 R2：6ml×1 | Price: €168.28 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 30ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Alkaline phosphatase Catalog: SC21A160 | Size: R1：32ml×4 R2：8ml×4 | Price: €106.5 Supplier: Szybio Lambert

ASK
Volume of reagent in a kit 160ml Test field of this automate Liver Function Reagents Insruments of IVD used for this reagent for Hitachi (7170/917) series and Olympus AU (400/600/640/100/2700/5400) series and Abbott Aerost and Siemens Advia (1200/2400) series and Bayer 1650 ; B: Hitachi 7060/7150/902/911 and Abbott Aeroset (C8000/ C16000) and Shimadzu (CL7200/7300/8000) and Olympus AU800 and Tosshiba 120FR and Sysmex Chemix 180, H: Hitachi 7020/902, C: Beckman, F: Toshiba 40, W: Toshiba 120, D: Dimension ; N: Mindray 200 ; L: Mindray 300 ; M: Mindray 400, T: Dupont.
Kiaa1704 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV199015 | Size: 1.0 µg DNA | Price: €621.36 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alkaline phosphatase antibody Catalog: GWB-45EB8D | Size: 1 x 1 vial | Price: €682 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Alppl2 antibody Catalog: GWB-MP230E | Size: 1 vial | Price: €625.56 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
uid :
250

name :
ALPP

description :
alkaline phosphatase, placental

chromosome :
2

geneticsource :
genomic

maplocation :
2q37.1

otheraliases :
ALP, PALP, PLAP, PLAP-1

otherdesignations :
alkaline phosphatase, placental type|alkaline phosphatase Regan isozyme|alkaline phosphomonoesterase|glycerophosphatase|placental alkaline phosphatase 1

nomenclaturesymbol :
ALPP

nomenclaturename :
alkaline phosphatase, placental

nomenclaturestatus :
Official

geneweight :
9731

chrsort :
02

chrstart :
232378533

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000002.12
chrstart: 232378533
chrstop: 232382888
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000002.12
chrstart: 232378533
chrstop: 232382888
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 233249416
chrstop: 233253771
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000002.12
chrstart: 232378533
chrstop: 232382888
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 233249416
chrstop: 233253771
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000002.12
chrstart: 232378533
chrstop: 232382888
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 233249520
chrstop: 233253771
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 233249520
chrstop: 233253771
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018913.1
chrstart: 232616057
chrstop: 232620309
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000045.1
chrstart: 227007505
chrstop: 227011756
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000002.11
chrstart: 233243347
chrstop: 233247598
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000045.1
chrstart: 227007505
chrstop: 227011756
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000002.10
chrstart: 232951591
chrstop: 232955842
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000045.1
chrstart: 227007505
chrstop: 227011756
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 225094116
chrstop: 225098367