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ALDH5A1: aldehyde dehydrogenase 5 family member A1

SSADH, SSDH

Summary

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)

ALDH5A1 description

Aldh5a1 peptide Catalog: ZP-4807 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

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Alternative name Aldh5A1 short protein sequence Gene target Aldh5A1 Peptide Technique peptide
Aldh5a1, 48-535aa, recombinant protein Catalog: GWB-P1315B | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 50ug:330,250ug:990 Store store in freezer for long therm or fridge for short time storage Category research antibodies, ELISAs, e. Coli rec. human proteins
Aldh5a1 rabbit polyclonal antibody Catalog: HOM-4807 | Size: 0.1 mg | Price: €513.9 Supplier: Zyagen

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Alternative name Aldh5A1 production species: rabbit polyclonal (Antibody to) Gene target Aldh5A1 Host Rabbit
Aldh5a1 antibody Catalog: GWB-MV659B | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Aldh5a1 human protein Catalog: GWB-BSP125 | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 2ug:83,10ug:182,1000ug:6809 Store store in freezer for long therm or fridge for short time storage Category research antibodies, ELISAs, e. Coli rec. human proteins
Aldh5a1 antibody Catalog: R36020-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

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Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Aldh5a1 antibody Catalog: R36177-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

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Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Anti-aldh5a1 / ssadh (n-term) antibody Catalog: AP11468PU-N | Size: 0,4 ml | Price: €704.81 Supplier: acr

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Category primary antibody Raised in Rabbit Clone 1 vial
Anti-aldh5a1 / ssadh (c-term) antibody Catalog: AP11469PU-N | Size: 0,4 ml | Price: €704.81 Supplier: acr

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Category primary antibody Raised in Rabbit Clone 1 vial
Anti-aldh5a1 / ssadh (485-496) antibody Catalog: AP22390PU-N | Size: 0,1 mg | Price: €669.99 Supplier: acr

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Category primary antibody Raised in Goat Clone 1 vial
Anti-aldh5a1 / ssadh (c-term) antibody Catalog: AP23122PU-N | Size: 50 Вµg | Price: €878.91 Supplier: acr

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Category primary antibody Raised in Rabbit Clone 1 vial
Anti-aldh5a1 / ssadh control peptide antibody Catalog: AP30045CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

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Category control peptide Raised in laboratory Clone 1 vial
Anti-aldh5a1 / ssadh (48-535, his-tag) antibody Catalog: AR09661PU-L | Size: 0,25 mg | Price: €1366.4 Supplier: acr

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Category antigen Raised in laboratory Clone 1 vial
Anti-aldh5a1 / ssadh (48-535, his-tag) antibody Catalog: AR09661PU-N | Size: 50 Вµg | Price: €582.34 Supplier: acr

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Category antigen Raised in laboratory Clone 1 vial
Anti-aldh5a1 antibody Catalog: 4807 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

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Gene info Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist. Gene names Aldh5A1 Antibody: SSDH, SSADH, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1 Antibodie's label unlabelled serum
Anti-aldh5a1 antibody Catalog: 42-676 | Size: 0.1 mg | Price: €216.13 Supplier: proscience

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Gene names ALDH5A1, succinate-semialdehyde dehydrogenase, SSDH, SSADH, NAD(+)-dependent succinic semialdehyde dehydrogenase, mitochondrial succinate semialdehyde dehydrogenase, aldehyde dehydrogenase 5A1, aldehyde dehydrogenase 5 family, member A1 Antibodie's label unlabelled serum Purity ALDH5A1 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Anti-aldh5a1 antibody Catalog: 42-677 | Size: 0.1 mg | Price: €216.13 Supplier: proscience

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Gene names ALDH5A1, succinate-semialdehyde dehydrogenase, SSDH, SSADH, NAD(+)-dependent succinic semialdehyde dehydrogenase, mitochondrial succinate semialdehyde dehydrogenase, aldehyde dehydrogenase 5A1, aldehyde dehydrogenase 5 family, member A1 Antibodie's label unlabelled serum Purity ALDH5A1 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Aldh5a1 antibody Catalog: 70R-9824 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Neuroscience
Aldh5a1 antibody Catalog: 70R-15671 | Size: 50 µl | Price: €614.76 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Proteases, Inhibitors, & Enzymes
Aldh5a1 blocking peptide Catalog: 33R-1160 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

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Category Proteins Antibody Subtype Blocking Peptides Area of research Neuroscience
Aldh5a1 protein his tag Catalog: 80R-1485 | Size: 50 µg | Price: €437.05 Supplier: fitzgerald

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Category Proteins Antibody Subtype Conjugated Proteins Area of research Nutrition & Metabolism
Elisa kit for human succinate-semialdehyde dehydrogenase, mitochondrial (aldh5a1) Catalog: E11322h | Size: 96 tests | Price: €730.03 Supplier: eiaab elisas

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Category ELISA Kit Target Succinate-semialdehyde dehydrogenase, mitochondrial Target's other names Homo sapiens, Human, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, ALDH5A1, SSADH, 1.2.1.24
Elisa kit for mouse succinate-semialdehyde dehydrogenase, mitochondrial (aldh5a1) Catalog: E11322m | Size: 96 tests | Price: €887.32 Supplier: eiaab elisas

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Category ELISA Kit Target Succinate-semialdehyde dehydrogenase, mitochondrial Target's other names Mus musculus, Mouse, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Aldh5a1, 1.2.1.24
Elisa kit for rat succinate-semialdehyde dehydrogenase, mitochondrial (aldh5a1) Catalog: E11322r | Size: 96 tests | Price: €887.32 Supplier: eiaab elisas

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Category ELISA Kit Target Succinate-semialdehyde dehydrogenase, mitochondrial Target's other names Rattus norvegicus, Rat, Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Aldh5a1, Ssadh, 1.2.1.24
Aldh5a1 recombinant protein Catalog: OPCA01462 | Size: one vial | Price: €425.05 Supplier: aviva

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Storage For short term storage ALDH5A1 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius. Tips Due to handling and transportation, small amounts of the ALDH5A1 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance. Alternative name ALDH5A1 recombinant Protein
Aldh5a1 recombinant protein Catalog: OPCA02588 | Size: one vial | Price: €425.05 Supplier: aviva

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Storage For short term storage ALDH5A1 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius. Tips Due to handling and transportation, small amounts of the ALDH5A1 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance. Alternative name ALDH5A1 recombinant Protein
Aldh5a1 protein Catalog: OPPA02485 | Size: one vial | Price: €206.52 Supplier: aviva

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Storage For short term storage ALDH5A1 Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius. Tips Due to handling and transportation, small amounts of the ALDH5A1 Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance. Alternative name ALDH5A1 Protein
Aldh5a1 antibody - middle region Catalog: ARP59587_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen ALDH5A1 - middle region Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody - n-terminal region Catalog: OAAB01221 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 - N-terminal region Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody - c-terminal region Catalog: OAAB01222 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 - C-terminal region Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OAAB01223 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OAEB02320 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OAEB02321 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OALA03914 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OALA07343 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OALA07344 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OALA08371 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OALA09184 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen ALDH5A1 Product type Antibody Gene name ALDH5A1
Aldh5a1 antibody Catalog: OAPB00755 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen Aldh5A1 Product type Antibody Gene name Aldh5A1
Anti-aldh5a1 antibody Catalog: 6750-100 | Size: ALDH5A1 Antibody | Price: €379.42 Supplier: Biovision

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Target of this antibody: ALDH5A1 Alternative names of antibody target: ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 members A1; NAD (+)-dependent succinic semialdehyde dehydrogenase. Background information: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 (aldehyde dehydrogenase 5 family, member A1), also known as SSDH or SSADH, is a 535 amino acid protein that localizes to the mitochondria and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH5A1 is required for gamma-aminobutyric acid (GABA) recycling from the synaptic cleft. Mutations of ALDH5A1 lead to succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) that is characterized by severe ataxia and by mildly retarded psychomotor development.
Anti-aldh5a1 antibody (ct) Catalog: 6751-100 | Size: ALDH5A1 Antibody (CT) | Price: €379.42 Supplier: Biovision

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Target of this antibody: ALDH5A1 Alternative names of antibody target: ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 members A1; NAD (+)-dependent succinic semialdehyde dehydrogenase. Background information: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH5A1 (aldehyde dehydrogenase 5 family, member A1), also known as SSDH or SSADH, is a 535 amino acid protein that localizes to the mitochondria and belongs to the aldehyde dehydrogenase family. Expressed in a variety of tissues, including liver, heart, lung, brain, kidney and placenta, ALDH5A1 is required for gamma-aminobutyric acid (GABA) recycling from the synaptic cleft. Mutations of ALDH5A1 lead to succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) that is characterized by severe ataxia and by mildly retarded psychomotor development.
uid :
7915

name :
ALDH5A1

description :
aldehyde dehydrogenase 5 family member A1

chromosome :
6

geneticsource :
genomic

maplocation :
6p22.3

otheraliases :
SSADH, SSDH

otherdesignations :
succinate-semialdehyde dehydrogenase, mitochondrial|NAD(+)-dependent succinic semialdehyde dehydrogenase|mitochondrial succinate semialdehyde dehydrogenase

nomenclaturesymbol :
ALDH5A1

nomenclaturename :
aldehyde dehydrogenase 5 family member A1

nomenclaturestatus :
Official

geneweight :
6265

chrsort :
06

chrstart :
24494968

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