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AKT1: AKT serine/threonine kinase 1

AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA

Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]

Organism: human (Homo sapiens)

AKT1 description

Pkakt1/pkba human Catalog: GWB-6B3B71 | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 5ug:523,20ug:1183,40ug:2486 Old catalog number 10-663-45529 Store store in freezer for long therm or fridge for short time storage
Akt1 (ser473 + tyr474) antibody, alexa fluor 488 Catalog: bs-10134R-A488 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name AKT1 (Ser473 + Tyr474) Antibody, ALEXA FLUOR 488 Conjugated Also known as Anti-AKT1 Ser473 + Tyr474 PAb ALEXA FLUOR 488 Category Conjugated Primary Antibodies
Anti-akt antibody Catalog: A03A0157 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

ASK
The antibodie's description anti-AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1 antibody The antigen used epitope of the human, mouse, rat AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1 antigen Gene name AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1
Akt1 antibody Catalog: GWB-C6A8F0 | Size: 1 vial | Price: €493.49 Supplier: genways

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Old catalog number 18-003-42910 Storage temperature store cold Expiry date 1 y
Akt1/2/3 (tyr474) antibody, alexa fluor 350 Catalog: bs-10133R-A350 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name AKT1/2/3 (Tyr474) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated Also known as Anti-AKT1/2/3 Tyr474 PAb ALEXA FLUOR 350 Category Conjugated Primary Antibodies
Akt1s1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV072606 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

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DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Akt1/2/3 (thr305/308/309) antibody, alexa fluor 488 Catalog: bs-5182R-A488 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name AKT1/2/3 (Thr305/308/309) Antibody, ALEXA FLUOR 488 Conjugated Also known as Anti-AKT1/2/3 (Thr305/308/309) PAb ALEXA FLUOR 488 Category Conjugated Primary Antibodies
V-akt murine thymoma viral oncogene homolog 1 (akt1) rabbit antibody to or anti-human polyclonal (pthr308) antibody Catalog: GWB-C6FE03 | Size: 1 vial | Price: €722.82 Supplier: genways

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Old catalog number 18-464-436280 Storage temperature store cold Expiry date 1 y
Akt1/2/3 (ser472/ser473/ser474) antibody, alexa fluor 555 Catalog: bs-0876R-A555 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name AKT1/2/3 (Ser472/Ser473/Ser474) Antibody, ALEXA FLUOR 555 Conjugated Also known as Anti-AKT1/2/3 (Ser472/Ser473/Ser474) PAb ALEXA FLUOR 555 Category Conjugated Primary Antibodies
Akt1/3 antibody Catalog: bs-0115M | Size: 0.1ml | Price: €315.78 Supplier: Bioss Primary Unconjugated Antibodies

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Long name AKT1/3 Primary Polyclonal Antibody Also known as AKT1/3 PAb Category Primary Antibodies
Anti-akt1 (phospho-thr450) antibody Catalog: A03A0160 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

ASK
The antibodie's description anti-AKT; AKT1 kinase; C-AKT; EC 2.7.11.1; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha antibody The antigen used epitope of the human:T450, mouse:T450, rat:T450 AKT; AKT1 kinase; C-AKT; EC 2.7.11.1; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha antigen Gene name AKT; AKT1 kinase; C-AKT; EC 2.7.11.1; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha
Antibody to or anti-akt phospho specificity ps473 antibody Catalog: GWB-B1604C | Size: 1 vial | Price: €800.87 Supplier: genways

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Old catalog number 18-732-292365 Storage temperature store cold Expiry date 1 y
Human akt1 (phospho-thr450) antibody Catalog: GWB-ASB086 | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 50ug:198,100ug:330 Store store in freezer for long therm or fridge for short time storage Category research antibodies, ELISAs, e. Coli rec. human proteins
Anti-akt1 (phospho-thr308) antibody Catalog: A03A0159 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

ASK
The antibodie's description anti-AKT; AKT1 kinase; C-AKT; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha antibody The antigen used epitope of the human:T308, mouse:T308, rat:T308 AKT; AKT1 kinase; C-AKT; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha antigen Gene name AKT; AKT1 kinase; C-AKT; kinase Akt1; PKB; PKB-alpha; Protein kinase B; RAC; RAC-alpha serine/threonine kinase; RAC-PK-alpha
Akt1/3 antibody, alexa fluor 594 Catalog: bs-0115R-A594 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name AKT1/3 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated Also known as Anti-AKT1/3 PAb ALEXA FLUOR 594 Category Conjugated Primary Antibodies
Akt1 peptide Catalog: ZP-3519 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

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Alternative name v-akt murine thymoma viral oncogene homolog 1 short protein sequence Gene target Akt1 Peptide Technique peptide
Akt1 inactive human recombinant protein Catalog: GWB-PSB79D | Size: 1 vial | Price: €583.54 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Akt1/3 antibody, alexa fluor 647 Catalog: bs-0115R-A647 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AKT1/3 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated Also known as Anti-AKT1/3 PAb ALEXA FLUOR 647 Category Conjugated Primary Antibodies
Akt1/2/3 (tyr474) antibody, alexa fluor 488 Catalog: bs-10133R-A488 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AKT1/2/3 (Tyr474) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated Also known as Anti-AKT1/2/3 Tyr474 PAb ALEXA FLUOR 488 Category Conjugated Primary Antibodies
Akt1/2/3 (ser472/ser473/ser474) antibody Catalog: bs-0876R | Size: 0.1ml | Price: €337.4 Supplier: Bioss Primary Unconjugated Antibodies

ASK
Long name AKT1/2/3 (Ser472/Ser473/Ser474) Antibody Also known as AKT1/2/3 (Ser472/Ser473/Ser474) Antibody Category Primary Antibodies
Akt1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV072595 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Akt1 (ser473 + tyr474) antibody, alexa fluor 647 Catalog: bs-10134R-A647 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AKT1 (Ser473 + Tyr474) Antibody, ALEXA FLUOR 647 Conjugated Also known as Anti-AKT1 Ser473 + Tyr474 PAb ALEXA FLUOR 647 Category Conjugated Primary Antibodies
Akt1 antibody (n-terminus) Catalog: GWB-291F70 | Size: 1 x 1 vial | Price: €564.33 Supplier: genways

ASK
Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Anti-akt1/3 (phospho-tyr437/434) antibody Catalog: A03A0164 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

ASK
The antibodie's description anti- EC 2.7.11.1; RAC-PK-alpha; Protein kinase B; PKB; C-AKT antibody The antigen used epitope of the human:Y437/434, mouse:Y437/434, rat:Y437/434 EC 2.7.11.1; RAC-PK-alpha; Protein kinase B; PKB; C-AKT antigen Gene name EC 2.7.11.1; RAC-PK-alpha; Protein kinase B; PKB; C-AKT
Akt1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV072596 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Akt1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV072598 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Akt1 (ser473 + tyr474) antibody, alexa fluor 594 Catalog: bs-10134R-A594 | Size: 100ul | Price: €420.43 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

ASK
Long name AKT1 (Ser473 + Tyr474) Antibody, ALEXA FLUOR 594 Conjugated Also known as Anti-AKT1 Ser473 + Tyr474 PAb ALEXA FLUOR 594 Category Conjugated Primary Antibodies
uid :
207

name :
AKT1

description :
AKT serine/threonine kinase 1

chromosome :
14

geneticsource :
genomic

maplocation :
14q32.33

otheraliases :
AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA

otherdesignations :
RAC-alpha serine/threonine-protein kinase|AKT1m|PKB alpha|RAC-PK-alpha|protein kinase B alpha|proto-oncogene c-Akt|rac protein kinase alpha|serine-threonine protein kinase|v-akt murine thymoma viral oncogene homolog 1|v-akt murine thymoma viral oncogene-like protein 1

nomenclaturesymbol :
AKT1

nomenclaturename :
AKT serine/threonine kinase 1

nomenclaturestatus :
Official

geneweight :
266071

chrsort :
14

chrstart :
104769348

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000014.9
chrstart: 104795742
chrstop: 104769348
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000014.9
chrstart: 104795742
chrstop: 104769348
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018925.2
chrstart: 105200088
chrstop: 105173738
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000014.9
chrstart: 104795742
chrstop: 104769348
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018925.2
chrstart: 105200088
chrstop: 105173738
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000014.9
chrstart: 104795742
chrstop: 104769348
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018925.2
chrstart: 105200088
chrstop: 105173738
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018925.2
chrstart: 105200088
chrstop: 105173738
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018925.1
chrstart: 86250895
chrstop: 86226644
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000057.1
chrstart: 85317153
chrstop: 85290759
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000014.8
chrstart: 105262079
chrstop: 105235685
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000057.1
chrstart: 85317153
chrstop: 85290759
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85464211
chrstop: 85432616
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000014.7
chrstart: 104333124
chrstop: 104306730
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000057.1
chrstart: 85317153
chrstop: 85290759
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000146.1
chrstart: 85456858
chrstop: 85432616