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All about genes

AIRE: autoimmune regulator

AIRE1, APECED, APS1, APSI, PGA1

Summary

This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]

Organism: human (Homo sapiens)

AIRE description

Anti-human furin Catalog: 101-M423 | Size: 100ug | Price: €403.44 Supplier: Reliatech antibodies

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Gene Name Furin Species Reactivity Human (Homo sapiens) Synonyms FURIN; FUR; PACE; SPC1; PCSK3
Anti-aire antibody Catalog: A02A0130 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

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The antibodie's description anti-Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED antibody The antigen used epitope of the human, mouse Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED antigen Gene name Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED
Colon tumor tissue array - 16 cases of colon cancer, each in duplicates, paired with adjacent normal tissues. Catalog: Z7020035 | Size: 5 slides | Price: €1167.08 Supplier: BioChain

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Shipping conditions Ambient Temperature Category Tissue SubCategory Paraffin Tissue Array
Cdk17 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV795994 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

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DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Cdk16 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV795990 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

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DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Pax1 antibody Catalog: GWB-ML806E | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Cdk14 antibody, alexa fluor 647 Catalog: bs-9078R-A647 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

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Long name CDK14 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated Also known as Anti-CDK14 PAb ALEXA FLUOR 647 Category Conjugated Primary Antibodies
Cdk14 antibody Catalog: GWB-MW426C | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Pctaire1 antibody Catalog: GWB-429437 | Size: 1 x 1 vial | Price: €709.61 Supplier: genways

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Old catalog number 20-272-190353 Storage temperature store cold Expiry date 1 y
Paired basic amino acid cleaving system 4 (pace4) (pcsk6) rabbit antibody to or anti-human polyclonal antibody Catalog: GWB-777F03 | Size: 1 tube | Price: €722.82 Supplier: genways

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Old catalog number 18-464-435482 Storage temperature store cold Expiry date 1 y
Cdk14 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV114798 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

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DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Prop1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV273841 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

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DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="http://xelonet.com/abm/" target="_blank" title="http://xelonet.com/abm/"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Furin lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV797987 | Size: 1.0 µg DNA | Price: €1350.79 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Cdk15 over-expression lysate reagent Catalog: GWB-E026E3 | Size: 1 vial | Price: €555.92 Supplier: genways

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Old catalog number 36-614-465416 Storage temperature store cold Expiry date 1 y
Cdk14 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV114797 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Rectum tumor tissue array - 16 cases of rectum cancer, each in duplicates, paired with adjacent normal tissues Catalog: Z7020042 | Size: 5 slides | Price: €1167.08 Supplier: BioChain

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Shipping conditions Ambient Temperature Category Tissue SubCategory Paraffin Tissue Array
Apeced protein (aire) goat antibody to or anti-human polyclonal (c- terminus) antibody Catalog: GWB-98F7DB | Size: 1 vial | Price: €722.82 Supplier: genways

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Old catalog number 18-464-436053 Storage temperature store cold Expiry date 1 y
Matrix protein ( 3-15 ) [zaire ebolavirus] 10mg Catalog: A1080-10 | Size: 10mg | Price: €444.26 Supplier: Ape

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This substance is also known as matrix protein ( 3-15 ) [Zaire ebolavirus] 10 milligrams of pure chemical substance for laboratory research. This product has a molecular weight of g/mol 1515.77 The molecular formula is C69H110N16O20S
Pitx1 antibody Catalog: GWB-668367 | Size: 1 tube | Price: €493.49 Supplier: genways

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Old catalog number 18-003-43192 Storage temperature store cold Expiry date 1 y
Paired box gene 5 antibody Catalog: PA20058RA | Size: 100ug | Price: €713.22 Supplier: AbELISA Antibodies

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Long name Rabbit anti-Human Paired Box Gene 5 (PAX5) polyclonal antibody Also known as Human Paired Box Gene 5 (PAX5) antibody Gen name PAX5
Human pitx1 antibody Catalog: GWB-ASD581 | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 50ug:198,100ug:330 Store store in freezer for long therm or fridge for short time storage Category research antibodies, ELISAs, e. Coli rec. human proteins
Pctk1 antibody Catalog: GWB-MX376G | Size: 1 vial | Price: €625.56 Supplier: genways

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Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Pctk3 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV809539 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Aire antibody Catalog: GWB-3D443F | Size: 1 x 1 vial | Price: €583.54 Supplier: genways

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Old catalog number 18-003-42261 Storage temperature store cold Expiry date 1 y
Cdk18 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV796000 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Human aire antibody Catalog: GWB-ASD303 | Size: Ask | Price: Ask Supplier: genways bulk

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Available sizes 50ug:198,100ug:330 Store store in freezer for long therm or fridge for short time storage Category research antibodies, ELISAs, e. Coli rec. human proteins
Pctk3 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV809536 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

ASK
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a> Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
uid :
326

name :
AIRE

description :
autoimmune regulator

chromosome :
21

geneticsource :
genomic

maplocation :
21q22.3

otheraliases :
AIRE1, APECED, APS1, APSI, PGA1

otherdesignations :
autoimmune regulator|autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein

nomenclaturesymbol :
AIRE

nomenclaturename :
autoimmune regulator

nomenclaturestatus :
Official

geneweight :
24667

chrsort :
21

chrstart :
44285837

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000021.9
chrstart: 44285837
chrstop: 44298218
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000021.9
chrstart: 44285837
chrstop: 44298218
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018932.2
chrstart: 45266543
chrstop: 45278924
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000021.9
chrstart: 44285837
chrstop: 44298218
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018932.2
chrstart: 45266543
chrstop: 45278924
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000021.9
chrstart: 44285837
chrstop: 44298218
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076210
chrstop: 31088674
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018932.2
chrstart: 45266543
chrstop: 45278924
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000021.8
chrstart: 45705720
chrstop: 45718101
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076210
chrstop: 31088674
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018932.2
chrstart: 45266543
chrstop: 45278924
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000021.8
chrstart: 45705720
chrstop: 45718101
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076210
chrstop: 31088674
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018932.1
chrstart: 36202728
chrstop: 36215109
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000021.8
chrstart: 45705720
chrstop: 45718101
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076210
chrstop: 31088674
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000021.8
chrstart: 45705762
chrstop: 45718109
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076252
chrstop: 31088682
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000021.8
chrstart: 45705762
chrstop: 45718109
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000064.1
chrstart: 30811016
chrstop: 30823363
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076252
chrstop: 31088682
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000021.8
chrstart: 45705762
chrstop: 45718109
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000064.1
chrstart: 30811016
chrstop: 30823363
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076252
chrstop: 31088682
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000021.7
chrstart: 44530190
chrstop: 44542529
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000064.1
chrstart: 30811016
chrstop: 30823355
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000153.1
chrstart: 31076252
chrstop: 31088674