The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Gene info Dioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. AHRR represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, AHRR can bind to nuclear factor <a href="http://kappa-B.Dioxin" target="_blank" title="kappa-B.Dioxin"><i class="fa fa-external-link" aria-hidden="true"></i></a> is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.Gene names AHRR, AHH, AHHR, KIAA1234, MGC167813, MGC176630, bHLHe77Antibodie's label unlabelled serum
The ELISA's description AHRR ELISA for Epigenetics and Nuclear Signaling researchScientific field AHRR ELISA for Epigenetics and Nuclear Signaling researchDomain Epigenetics and Nuclear Signaling
Storage For short term storage AHRR Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the AHRR Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name AHRR recombinant Protein
Short description of the assay Sandwich ELISA for determination of the concentration of Aryl Hydrocarbon Receptor RepressorAntigen concentration that can be measured 0.156-10ng per mlTarget antigen Aryl Hydrocarbon Receptor Repressor
Other name AHH; AHHR; BHLHE77; Aryl Hydrocarbon Receptor Regulator; Class E basic helix-loop-helix protein 77Immunogen AHRR (Met1~Pro182)Verified reactivity Homo sapiens (Human)
Cell line type 293TNCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type 293NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HepG2NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MCF7NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type K562NCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type U87-MGNCBI number NM_020731Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU000504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU050504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h00504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h50504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h00504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h50504 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
uid :
57491
name :
AHRR
description :
aryl-hydrocarbon receptor repressor
chromosome :
5
geneticsource :
genomic
maplocation :
5p15.33
otheraliases :
AHH, AHHR, bHLHe77
otherdesignations :
aryl hydrocarbon receptor repressor|ahR repressor|aryl hydrocarbon hydroxylase regulator|class E basic helix-loop-helix protein 77|dioxin receptor repressor