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All about genes

AFDN: afadin, adherens junction formation factor

AF6, MLL-AF6, MLLT4, l-afadin

Summary

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]

Organism: human (Homo sapiens)

AFDN related publications

Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation.

AFDN description

adipsin antibody (d-3)

Catalog: sc-373860 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (D-3)

recommended for detection of Adipsin of mouse, rat and human origin by WB, IP, IF and ELISA

adipsin antibody (d-8)

Catalog: sc-376015 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (D-8)

recommended for detection of Adipsin of mouse, rat and human origin by WB, IP, IF and ELISA

adipsin antibody (d10/4)

Catalog: sc-47683 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (D10/4) Adipsin Antibody (D10/4) Adipsin Antibody (D10/4) Adipsin Antibody (D10/4)

recommended for detection of Adipsin of human origin by WB, IP, IF and IHC(P)

adipsin antibody (h-1)

Catalog: sc-271685 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (H-1)

recommended for detection of Adipsin of human origin by WB, IP, IF and ELISA

adipsin antibody (h13/11)

Catalog: sc-47735 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (H13/11)

recommended for detection of Adipsin of human origin by WB and IP

adipsin antibody (p-16)

Catalog: sc-12402 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin Antibody (P-16) Adipsin Antibody (P-16) Adipsin Antibody (P-16) Adipsin Antibody (P-16)

DISCONTINUED: recommended for detection of Adipsin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA

adipsin crispr knockout and activation products (h)

Catalog: sc-401782 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin CRISPR Knockout and Activation Products (h) Adipsin CRISPR Knockout and Activation Products (h) Adipsin CRISPR Knockout and Activation Products (h) Adipsin CRISPR Knockout and Activation Products (h)

human Adipsin-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

adipsin crispr knockout and activation products (m)

Catalog: sc-419011-KO-2 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin CRISPR Knockout and Activation Products (m) Adipsin CRISPR Knockout and Activation Products (m) Adipsin CRISPR Knockout and Activation Products (m) Adipsin CRISPR Knockout and Activation Products (m)

mouse Adipsin-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

adipsin sirna (h), shrna and lentiviral particle gene silencers

Catalog: sc-29646 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin siRNA (h), shRNA and Lentiviral Particle Gene Silencers Adipsin siRNA (h), shRNA and Lentiviral Particle Gene Silencers Adipsin siRNA (h), shRNA and Lentiviral Particle Gene Silencers

human Adipsin-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

adipsin sirna (m), shrna and lentiviral particle gene silencers

Catalog: sc-29647 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

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Adipsin siRNA (m), shRNA and Lentiviral Particle Gene Silencers Adipsin siRNA (m), shRNA and Lentiviral Particle Gene Silencers Adipsin siRNA (m), shRNA and Lentiviral Particle Gene Silencers

mouse Adipsin-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

Mhc class i h-2kb, mouse mouse monoclonal antibody-mouse; clone: af6-88.5, frozen,flow,ip, fitc conj. Catalog: YSRTMCA4731F | Size: 0.1 mg | Price: €297.77 Supplier: accurate-monoclonals

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Alternative name 1 MHC Class I H-2Kb, Mouse Mab anti-Mouse; Clone: AF6-88.5, frozen,flow,IP, FITC conj. Alternative name 2 MHC Class I H-2Kb, Mouse Mab antibody-Mouse; Clone: AF6-88.5, frozen,flow,IP, FITC conj. Alternative name 3 MHC Class I H-2Kb, Mus musculus Mab antibody-Mus musculus; Clone: AF6-88.5, frozen,flow,IP, FITC conj.
Myeloid/lymphoid or mixed-lineage leukemia translocated to 4 (mllt4)/ af6 rabbit antibody to or anti-human polyclonal (aa1582-1597) antibody Catalog: GWB-716FDD | Size: 1 tube | Price: €722.82 Supplier: genways

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Old catalog number 18-464-435649 Storage temperature store cold Expiry date 1 y
Mllt4 antibody Catalog: GWB-92F5DD | Size: 1 vial | Price: €493.49 Supplier: genways

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Old catalog number 18-003-44718 Storage temperature store cold Expiry date 1 y
Afadin antibody Catalog: bs-2754R | Size: 0.1ml | Price: €315.78 Supplier: Bioss Primary Unconjugated Antibodies

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Long name Afadin Primary Polyclonal Antibody Also known as Afadin PAb Category Primary Antibodies
Mhc class i h-2kb, mouse mouse monoclonal antibody-mouse; clone: af6-88.5, frozen,flow,ip Catalog: YSRTMCA4731 | Size: 0.25 mg | Price: €469.47 Supplier: accurate-monoclonals

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Alternative name 1 MHC Class I H-2Kb, Mouse Mab anti-Mouse; Clone: AF6-88.5, frozen,flow,IP Alternative name 2 MHC Class I H-2Kb, Mouse Mab antibody-Mouse; Clone: AF6-88.5, frozen,flow,IP Alternative name 3 MHC Class I H-2Kb, Mus musculus Mab antibody-Mus musculus; Clone: AF6-88.5, frozen,flow,IP
Anti-mllt4 / af6 / afadin (1814-1829) antibody Catalog: AM26175PU-N | Size: 0,1 mg | Price: €913.73 Supplier: acr

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Vial description Protein AF-6 Category primary antibody Clonality monoclonal
Anti-mllt4 antibody Catalog: 28-038 | Size: 100 ug | Price: €216.13 Supplier: proscience

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Gene info AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t (6;11) translocations. Gene names MLLT4, RP3-470B24.4, AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3 Antibodie's label unlabelled serum
Anti-mllt4 antibody Catalog: 49-700 | Size: 0.05 mg | Price: €216.13 Supplier: proscience

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Gene names MLLT4, Afadin, AF6, AF-6, Translocated to, 4, Protein AF-6, RP3-431P23.3 Antibodie's label unlabelled serum Purity Protein G Column
Mllt4 antibody Catalog: 20R-1086 | Size: 100 µg | Price: €488.68 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies Area of research Cancer
Mllt4 antibody Catalog: 70R-18534 | Size: 50 µl | Price: €614.76 Supplier: fitzgerald

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Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Signal Transduction
Mllt4 blocking peptide Catalog: 33R-3641 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

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Category Proteins Antibody Subtype Blocking Peptides Area of research Cancer
Myeloid/lymphoid or mixed-lineage leukemia translocated to 4 (mllt4) polyclonal antibody Catalog: ABP-PAB-10854 | Size: 100 ug | Price: €381.82 Supplier: allele

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Product category Orbigen You will recive this Ice Packs Product Family Qualified Antibodies
Guinea pig afadin(mllt4) elisa kit Catalog: E05A1920 | Size: 96 well immunosorbent assay kit (48 available) | Price: €866.91 Supplier: BlueGen ELISAs

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The ELISA's description MLLT4 ELISA for Neurobiology research Scientific field MLLT4 ELISA for Neurobiology research Domain Neurobiology
Mllt4 antibody - n-terminal region Catalog: ARP34225_T100 | Size: one vial | Price: €309.78 Supplier: aviva

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Recognized antigen MLLT4 - N-terminal region Product type Antibody Gene name MLLT4
Mllt4-as1 antibody - c-terminal region Catalog: ARP42769_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen MLLT4-AS1 - C-terminal region Product type Antibody Gene name MLLT4-AS1
Mllt4-as1 antibody - middle region Catalog: ARP70009_P050 | Size: one vial | Price: €375.82 Supplier: aviva

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Recognized antigen MLLT4-AS1 - middle region Product type Antibody Gene name MLLT4-AS1
Mllt4 antibody Catalog: OALA07089 | Size: one vial | Price: €509.1 Supplier: aviva

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Recognized antigen MLLT4 Product type Antibody Gene name MLLT4
Rassf1 (ras association (ralgds/af-6) domain family 1, aa536941, au044980, nore2a, rda32, reh3p21, rassf1a, rassf1b, rassf1c, rassf1) antibody Catalog: MBS619048 | Size: 100ug | Price: €611.16 Supplier: MBS Polyclonals

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Alternative name1 Anti-RASSF1 (Ras association (RalGDS/AF-6) domain family 1, AA536941, AU044980, NORE2A, RDA32, REH3P21, Rassf1A, Rassf1B, Rassf1C, Rassf1) Alternative name2 RASSF1 (Ras association (RalGDS/AF-6) domain family 1, AA536941, AU044980, NORE2A, RDA32, REH3P21, Rassf1A, Rassf1B, Rassf1C, Rassf1) Alternative name3 RASSF1 (Ras association (RalGDS/AF-6) domain family 1, AA536941, AU044980, NORE2A, RDA32, REH3P21, Rassf1A, Rassf1B, Rassf1C, Rassf1)
Anti-human mllt4 / afadin antibody Catalog: MBS241051 | Size: 50ug | Price: €716.82 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit Polyclonal to Human MLLT4 / Afadin Alternative name2 Rabbit PAb to Human MLLT4 / Afadin Alternative name3 Lapin Polyclonal to Homo sapiens MLLT4 / Afadin
Anti-human ras association (ralgds/af-6) domain family (n-terminal) member 7 pab Catalog: MBS711002 | Size: 0.05 ml | Price: €557.12 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 polyclonal Antibody Alternative name2 Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 PAb Alternative name3 Lapin anti-Homo sapiens Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 polyclonal Antibody
Anti-human ras association (ralgds/af-6) domain family (n-terminal) member 8 pab Catalog: MBS711343 | Size: 0.05 ml | Price: €557.12 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 polyclonal Antibody Alternative name2 Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 PAb Alternative name3 Lapin anti-Homo sapiens Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 polyclonal Antibody
Anti-human ras association (ralgds/af-6) domain family (n-terminal) member 9 pab Catalog: MBS713273 | Size: 150ul | Price: €1008.59 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 polyclonal Antibody Alternative name2 Rabbit anti-human Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 PAb Alternative name3 Lapin anti-Homo sapiens Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 polyclonal Antibody
Anti-human ras association (ralgds/af-6) domain family member 4 pab Catalog: MBS712432 | Size: 0.05 ml | Price: €557.12 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit anti-human Ras association (RalGDS/AF-6) domain family member 4 polyclonal Antibody Alternative name2 Rabbit anti-human Ras association (RalGDS/AF-6) domain family member 4 PAb Alternative name3 Lapin anti-Homo sapiens Ras association (RalGDS/AF-6) domain family member 4 polyclonal Antibody
Anti-human ras association (ralgds/af-6) domain family member 6 pab Catalog: MBS712574 | Size: 0.05 ml | Price: €557.12 Supplier: MBS Polyclonals

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Alternative name1 Anti-Rabbit anti-human Ras association (RalGDS/AF-6) domain family member 6 polyclonal Antibody Alternative name2 Rabbit anti-human Ras association (RalGDS/AF-6) domain family member 6 PAb Alternative name3 Lapin anti-Homo sapiens Ras association (RalGDS/AF-6) domain family member 6 polyclonal Antibody
Human mllt4 crispr knock out 293 cell line Catalog: K1308552 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out a549 cell line Catalog: K1308553 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type A549 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out 293t cell line Catalog: K1308551 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type 293T NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out hela cell line Catalog: K1308554 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HeLa NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out mda-mb-435 cell line Catalog: K1308555 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MDA-MB-435 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out hepg2 cell line Catalog: K1308556 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type HepG2 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out mcf7 cell line Catalog: K1308557 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type MCF7 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out k562 cell line Catalog: K1308558 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type K562 NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human mllt4 crispr knock out u87-mg cell line Catalog: K1308559 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

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Cell line type U87-MG NCBI number NM_005936 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Mllt4 3'utr luciferase stable cell line Catalog: TU014357 | Size: 1 ml | Price: €2612.72 Supplier: ABM microrna

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Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #TU014357 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Mllt4 3'utr gfp stable cell line Catalog: TU064357 | Size: 1 ml | Price: €2612.72 Supplier: ABM microrna

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Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #TU064357 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Mllt4 3'utr lenti-reporter-luc virus Catalog: MV-h14357 | Size: 3 ml | Price: €1819.06 Supplier: ABM microrna

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Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MV-h14357 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Mllt4 3'utr lenti-reporter-gfp virus Catalog: MV-h64357 | Size: 3 ml | Price: €1819.06 Supplier: ABM microrna

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Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MV-h64357 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
uid :
4301

name :
AFDN

description :
afadin, adherens junction formation factor

chromosome :
6

geneticsource :
genomic

maplocation :
6q27

otheraliases :
AF6, MLL-AF6, MLLT4, l-afadin

otherdesignations :
afadin|ALL1-fused gene from chromosome 6 protein|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4|myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4|protein AF-6

nomenclaturesymbol :
AFDN

nomenclaturename :
afadin, adherens junction formation factor

nomenclaturestatus :
Official

geneweight :
6966

chrsort :
06

chrstart :
167826871

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000006.12
chrstart: 167826871
chrstop: 167972022
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000006.12
chrstart: 167826871
chrstop: 167972022
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018917.2
chrstart: 168490725
chrstop: 168635427
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000006.12
chrstart: 167826921
chrstop: 167972022
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018917.2
chrstart: 168490725
chrstop: 168635427
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000006.12
chrstart: 167826921
chrstop: 167972022
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800384
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018917.2
chrstart: 168490725
chrstop: 168635427
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000006.11
chrstart: 168227601
chrstop: 168372702
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800384
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018917.2
chrstart: 168490725
chrstop: 168635427
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000006.11
chrstart: 168227670
chrstop: 168372699
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800384
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018917.1
chrstart: 168276171
chrstop: 168383767
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000006.11
chrstart: 168227670
chrstop: 168372699
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800384
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000006.11
chrstart: 168227670
chrstop: 168372699
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800384
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000006.11
chrstart: 168227670
chrstop: 168365792
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000049.1
chrstart: 168944732
chrstop: 169081689
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165793477
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000006.11
chrstart: 168227670
chrstop: 168372702
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000049.1
chrstart: 168944732
chrstop: 169088599
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693042
chrstop: 165800387
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000006.10
chrstart: 167970519
chrstop: 168115551
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000049.1
chrstart: 168944732
chrstop: 169088599
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000138.1
chrstart: 165693044
chrstop: 165800387