ADAMTS8: ADAM metallopeptidase with thrombospondin type 1 motif 8
ADAM-TS8, METH2
Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab anti-Human, Rhesus, FITC; flowAlternative name 2 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Human, Rhesus, FITC; flowAlternative name 3 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Homo sapiens, Rhesus, FITC; flow
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab anti-Human, Rhesus; frozen, IH/flowAlternative name 2 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Human, Rhesus; frozen, IH/flowAlternative name 3 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Homo sapiens, Rhesus; frozen, IH/flow
Alternative name 1 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab anti-Human, Rhesus; frozen, IH/flowAlternative name 2 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Human, Rhesus; frozen, IH/flowAlternative name 3 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Homo sapiens, Rhesus; frozen, IH/flow
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://xelonet.com/abm/" target="_blank" title="http://xelonet.com/abm/"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab anti-Human, Rhesus, FITC; flowAlternative name 2 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Human, Rhesus, FITC; flowAlternative name 3 T-Cell Receptor V delta 1 (TCR-Vd 1), Clone: TS8, Mab antibody-Homo sapiens, Rhesus, FITC; flow
Gene names ADAMTS8, METH2, FLJ41712, ADAM-TS8, ADAM metallopeptidase with thrombospondin type 1 motif, 8, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifAntibodie's label unlabelled serumPurity ADAMTS8 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Gene names ADAMTS8, METH2, FLJ41712, ADAM-TS8, ADAM metallopeptidase with thrombospondin type 1 motif, 8, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifAntibodie's label unlabelled serumPurity ADAMTS8 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Category ELISA KitTarget A disintegrin and metalloproteinase with thrombospondin motifs 8Target's other names Homo sapiens, Human, A disintegrin and metalloproteinase with thrombospondin motifs 8, ADAM-TS 8, ADAM-TS8, ADAMTS-8, METH-2, METH-8, ADAMTS8, METH2, 3.4.24.-
Category ELISA KitTarget A disintegrin and metalloproteinase with thrombospondin motifs 8Target's other names Mus musculus, Mouse, A disintegrin and metalloproteinase with thrombospondin motifs 8, ADAM-TS 8, ADAM-TS8, ADAMTS-8, METH-2, Adamts8, 3.4.24.-
The ELISA's description ADAMTS8 ELISA for Cardiovascular researchScientific field ADAMTS8 ELISA for Cardiovascular researchType of ELISA competitive ELISA
Storage For short term storage ADAMTS8 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the ADAMTS8 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name ADAM metallopeptidase including thrombospondin classification 1 motif, 8 recombinant Protein
Short description of the assay Sandwich ELISA for determination of the concentration of A Disintegrin And Metalloproteinase With Thrombospondin 8Antigen concentration that can be measured 0.156-10ng per mlTarget antigen A Disintegrin And Metalloproteinase With Thrombospondin 8
Other name ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAM-TS8; FLJ41712; METH2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8Immunogen C-RQERGDHQEDVerified reactivity Thus antibody doesn't seem to cross react with other species. Please contact us for more information
Other name ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; ADAM-TS8; FLJ41712; METH2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8Immunogen C-QSSKERATTNVerified reactivity Thus antibody doesn't seem to cross react with other species. Please contact us for more information
Cell line type 293TNCBI number NM_007037Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type 293NCBI number NM_007037Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_007037Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_007037Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_007037Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
uid :
11095
name :
ADAMTS8
description :
ADAM metallopeptidase with thrombospondin type 1 motif 8
chromosome :
11
geneticsource :
genomic
maplocation :
11q24.3
otheraliases :
ADAM-TS8, METH2
otherdesignations :
A disintegrin and metalloproteinase with thrombospondin motifs 8|ADAMTS-8|METH-2|METH-8|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8
nomenclaturesymbol :
ADAMTS8
nomenclaturename :
ADAM metallopeptidase with thrombospondin type 1 motif 8