This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]
Long Name Human A Disintegrin And Metalloprotease 12 (ADAM12) ELISA KitRecognized antigen A Disintegrin And Metalloprotease 12 (ADAM12)Species reactivity Human (Homo sapiens)
Gene names Adam12, OTTMUSP00000023508, Mltna, mKIAA4001, meltrin-alpha, meltrin alpha, KIAA4001, disintegrin and metalloproteinase domain-containing protein 12, ADAM 12, a disintegrin and metalloproteinase domain 12 (meltrin alpha), a disintegrin and metalloprotease domain 12, a disintegrin and metallopeptidase domain 12 (meltrin alpha), MLTN, UNQ346/PRO545Antibodie's label unlabelled serumPurity Antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Gene names ADAM12, MCMP, MLTN, MLTNA, MCMPMltna, a disintegrin and metalloproteinase domain 12 (meltrin alpha), meltrin alpha, A disintegrin and metalloproteinase domain 12 (Meltrin-alpha, mouse, homolog of), UNQ346/PRO545Antibodie's label unlabelled serumPurity ADAM12 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Category ELISA KitTarget Disintegrin and metalloproteinase domain-containing protein 12Target's other names Homo sapiens, Human, Disintegrin and metalloproteinase domain-containing protein 12, ADAM 12, Meltrin-alpha, ADAM12, MLTN, UNQ346/PRO545, 3.4.24.-
Category ELISA KitTarget Disintegrin and metalloproteinase domain-containing protein 12Target's other names Mus musculus, Mouse, Disintegrin and metalloproteinase domain-containing protein 12, ADAM 12, Meltrin-alpha, Adam12, Mltna, 3.4.24.-
Storage For short term storage ADAM12 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the ADAM12 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name ADAM metallopeptidase domain 12 recombinant Protein
Storage For short term storage ADAM12 Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the ADAM12 Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name ADAM metallopeptidase domain 12 Protein
Target ADAM12Background A Disintegrin And Metalloprotease 12 (ADAM12) is also known as Meltrin-alpha and MCMP, is a member of the ADAM and MDC (Metalloprotease, Disintegrin, Cysteine-rich) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE. ADAM12 has four Isoform, Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. ADAM12 Involved in skeletal muscle regeneration, specifically at the onset of cell fusion and also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors.Concentration N/A
Short description of the assay Sandwich ELISA for determination of the concentration of A Disintegrin And Metalloprotease 12Antigen concentration that can be measured 0.156-10ng per mlLong name ELISA kit for A Disintegrin And Metalloprotease 12 (ADAM12)
Other name MCMP; MCMPMltna; MLTN; MLTNA; Meltrin Alpha; Disintegrin and metalloproteinase domain-containing protein 12Immunogen ADAM12 (Ser513~His767)Verified reactivity Homo sapiens (Human)
Other name ADAM12; ADAM metallopeptidase domain 12; MCMP; MCMPMltna; MLTN; MLTNA; disintegrin and metalloproteinase domain-containing protein 12; meltrin-alphaImmunogen C-REFQRQGKDLEKVKQVerified reactivity Human, Mouse, Rat, Pig
Other name Adam12; a disintegrin and metallopeptidase domain 12 (meltrin alpha); KIAA4001; Mltna; mKIAA4001; ADAM 12; OTTMUSP00000023508; a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase domain 12 (meltrin alpha); disintegrin and metaImmunogen KKTTMEKLRCVHPVerified reactivity Thus antibody doesn't seem to cross react with other species. Please contact us for more information
Other name ADAM12; MCMP; MLTN; MLTNA; MCMPMltna; a disintegrin and metalloproteinase domain 12 (meltrin alpha); meltrin alpha; A disintegrin and metalloproteinase domain 12 (Meltrin-alpha, mouse, homolog of); ADAM metallopeptidase domain 12; RP11-295J3.5Immunogen AARPLPVSPARALCVerified reactivity Human