Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Available sizes 50ug:440,250ug:1320Store store in freezer for long therm or fridge for short time storageCategory research antibodies, ELISAs, e. Coli rec. human proteins
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Gene info Short/branched chain acyl-CoA dehydrogenase (ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. ACADSB has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain <a href="http://acyl-CoAs.Short/branched" target="_blank" title="acyl-CoAs.Short/branched"><i class="fa fa-external-link" aria-hidden="true"></i></a> chain acyl-CoA dehydrogenase (ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-kDa. Sequence Note: The 3' UTR extension represented by the RefSeq transcript record was derived from genomic sequence data to optimize consistency to the reference genome assembly. The extent of the UTR extension and the location of the polyA site was based on transcript alignments.Gene names ACADSB, 2-MEBCAD, ACAD7, SBCADAntibodie's label unlabelled serum
Target of this antibody: ACADSBAlternative names of antibody target: Short/branched chain specific acyl-CoA dehydrogenase, SBCADBackground information: Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. ACADSB catalyzes the degradation of L-isoleucine and has the greatest affinity towards (S)-2-methylbutyryl-CoA, isobutyryl-CoA and 2-methylhexanoyl-CoA as substrates.
Target of this antibody: ACADSBAlternative names of antibody target: Short/branched chain specific acyl-CoA dehydrogenase, SBCADBackground information: Short/branched chain acyl-CoA dehydrogenase(ACADSB) belongs to the acyl-CoA dehydrogenase family of enzymes catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. ACADSB catalyzes the degradation of L-isoleucine and has the greatest affinity towards (S)-2-methylbutyryl-CoA, isobutyryl-CoA and 2-methylhexanoyl-CoA as substrates.
Other name Short/branched chain specific acyl-CoA dehydrogenase,mitochondrial,SBCAD,2-methyl branched chain acyl-CoA dehydrogenase,2-MEBCAD,2-methylbutyryl-coenzyme A dehydrogenase,2-methylbutyryl-CoA dehydrogenase,ACADSBImmunogen Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial protein (34-253AA)Verified reactivity Human, Rat
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uid :
36
name :
ACADSB
description :
acyl-CoA dehydrogenase short/branched chain
chromosome :
10
geneticsource :
genomic
maplocation :
10q26.13
otheraliases :
2-MEBCAD, ACAD7, SBCAD
otherdesignations :
short/branched chain specific acyl-CoA dehydrogenase, mitochondrial|2-methyl branched chain acyl-CoA dehydrogenase|2-methylbutyryl-coenzyme A dehydrogenase|acyl-Coenzyme A dehydrogenase, short/branched chain