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ACADM Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

Acadm lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV066671 | Size: 1.0 µg DNA | Price: €389.26 Supplier: ABM lentivectors

DNA lentivector for transduction information: Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files: Lentivirus references:

ACADM gene: acyl-CoA dehydrogenase medium chain

ACAD1, MCAD, MCADH

Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)