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ABCD4 CRISPR Knockout and Activation Products (h)

abcd4 crispr knockout and activation products (h) Catalog: sc-406750 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology ASK
 ABCD4 CRISPR Knockout and Activation Products (h)  ABCD4 CRISPR Knockout and Activation Products (h)  ABCD4 CRISPR Knockout and Activation Products (h)  ABCD4 CRISPR Knockout and Activation Products (h)

human ABCD4-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

ABCD4 gene: ATP binding cassette subfamily D member 4

ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in several protein-coding and non-protein-coding variants. [provided by RefSeq, Jul 2017]

Organism: human (Homo sapiens)