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anti-ABCC2 Antibody

Anti-abcc2 antibody Catalog: A01A0016 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies ASK
The antibodie's description: anti-Canalicular multispecific organic anion transporter 1;ATP-binding cassette sub-family C member 2;Canalicular multidrug resistance protein;Multidrug resistance-associated protein 2 ;ABCC2 ;CMOAT; CMOAT1; CMRP; MRP2 antibody The antigen used: epitope of the human Canalicular multispecific organic anion transporter 1;ATP-binding cassette sub-family C member 2;Canalicular multidrug resistance protein;Multidrug resistance-associated protein 2 ;ABCC2 ;CMOAT; CMOAT1; CMRP; MRP2 antigen Gene name: Canalicular multispecific organic anion transporter 1;ATP-binding cassette sub-family C member 2;Canalicular multidrug resistance protein;Multidrug resistance-associated protein 2 ;ABCC2 ;CMOAT; CMOAT1; CMRP; MRP2

ABCC2 gene: ATP binding cassette subfamily C member 2

ABC30, CMOAT, DJS, MRP2, cMRP

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)