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anti-AATF Antibody

Anti-aatf antibody Catalog: 28-979 | Size: 100 ug | Price: €216.13 Supplier: proscience ASK
Gene info: The AATF is a protein that was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced <a href="http://apoptosis.The" target="_blank" title="apoptosis.The"><i class="fa fa-external-link" aria-hidden="true"></i></a> protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. Gene names: AATF, DED, BFR2, CHE1, CHE-1 Antibodie's label: unlabelled serum

AATF gene: apoptosis antagonizing transcription factor

BFR2, CHE-1, CHE1, DED

Summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)