This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Alternative name 1 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab anti-Hu, cytospin/frozen/paraffinAlternative name 2 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffinAlternative name 3 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffin
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Alternative name 1 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab anti-Hu, cytospin/frozen/paraffinAlternative name 2 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffinAlternative name 3 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffin
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical files <a href="https://www.abmgood.com/UbC-Lentivirus-System.html" target="_blank" title="https://www.abmgood.com/UbC-Lentivirus-System.html"><i class="fa fa-external-link" aria-hidden="true"></i></a>Lentivirus references <a href="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf" target="_blank" title="http://compbio.dfci.harvard.edu/compbio/research/labprotocols/contentBlocks/0/contentBlock_files/file15/Lentivirus_Production_and_Transfection_Protocol.pdf"><i class="fa fa-external-link" aria-hidden="true"></i></a>
Storage For short term storage A2ML1 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius.Tips Due to handling and transportation, small amounts of the A2ML1 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance.Alternative name A2ML1 recombinant Protein
Short description of the assay Sandwich ELISA for determination of the concentration of Alpha-2-Macroglobulin Like Protein 1Antigen concentration that can be measured 0.78-50ng per mlLong name ELISA kit for Alpha-2-Macroglobulin Like Protein 1 (a2ML1)
Other name Alpha-2-macroglobulin-like protein 1,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9,A2ML1Immunogen Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)Verified reactivity Human
Alternative name1 Anti-A2ML1, NT (A2ML1, CPAMD9, Alpha-2-macroglobulin-like protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9)Alternative name2 A2ML1, NT (A2ML1, CPAMD9, Alpha-2-macroglobulin-like protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9)Alternative name3 A2ML1, NT (A2ML1, CPAMD9, Alpha-2-macroglobulin-like protein 1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9)
Cell line type 293TNCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type 293NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type A549NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HeLaNCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MDA-MB-435NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type HepG2NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type MCF7NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type K562NCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Cell line type U87-MGNCBI number NM_144670Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU000006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #TU050006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h00006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MV-h50006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h00006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply.Ordering If you wish to order this product, please include the catalogue number #MT-h50006 in your purchase order among with your shipping and billing information.Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Product type AdenovirusDetection and sensitivity Before using A2ML1 Adenovirus (Human) please read the package insert. It is intended for Human reactivity. Accession Number: NM_144670Performance and applications Please contact Gentaur's support by livechat, email or phone in order to receive the requested information. The product is for research use only.
Product type AdenovirusDetection and sensitivity Before using A2ML1-HA Adenovirus (Human) please read the package insert. It is intended for Human reactivity. Accession Number: NM_144670Performance and applications Please contact Gentaur's support by livechat, email or phone in order to receive the requested information. The product is for research use only.
Product type AdenovirusDetection and sensitivity Before using A2ML1-His Adenovirus (Human) please read the package insert. It is intended for Human reactivity. Accession Number: NM_144670Performance and applications Please contact Gentaur's support by livechat, email or phone in order to receive the requested information. The product is for research use only.
Original name Mouse Alpha-2-macroglobulin-like protein 1(A2ML1) ELISA kitReacts with mouse (Mus musculus)Assay sensitivity find more technical details in the user manual
uid :
144568
name :
A2ML1
description :
alpha-2-macroglobulin like 1
chromosome :
12
geneticsource :
genomic
maplocation :
12p13.31
otheraliases :
CPAMD9, p170
otherdesignations :
alpha-2-macroglobulin-like protein 1|C3 and PZP-like, alpha-2-macroglobulin domain containing 9