The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical filesLentivirus references
Alternative name 1 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab anti-Hu, cytospin/frozen/paraffinAlternative name 2 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffinAlternative name 3 Multi-Drug Resistance Related Protein (MDR), P-Glycoprotein P170, 170-180kD, Clone: JSB-1, Mab antibody-Hu, cytospin/frozen/paraffin
Available sizes 100ug:330,500ug:990Store store in freezer for long therm or fridge for short time storageCategory research antibodies, ELISAs, e. Coli rec. human proteins
Alternative name 1 CD91, Alpha-2-Macroglobulin Receptor, Clone: Alpha 2MR alpha-2, Mab anti-HumanAlternative name 2 CD91, Alpha-2-Macroglobulin Receptor, Clone: Alpha 2MR alpha-2, Mab antibody-HumanAlternative name 3 CD91, Alpha-2-Macroglobulin Receptor, Clone: Alpha 2MR alpha-2, Mab antibody-Homo sapiens
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical filesLentivirus references
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical filesLentivirus references
DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available.Lentiviral technical filesLentivirus references
Alternative name 1 CD91, Clone: A2Mr alpha-2, Mab anti-; RPEAlternative name 2 CD91, Clone: A2Mr alpha-2, Mab antibody-; RPEAlternative name 3 CD91, Clone: A2Mr alpha-2, Mab antibody-; RPE