array(1) { [0]=> object(AppBundle\Entity\geneTOpubmed)#305 (6) { ["id":"AppBundle\Entity\geneTOpubmed":private]=> int(63) ["geneNihId":"AppBundle\Entity\geneTOpubmed":private]=> int(23461) ["pubmedNihId":"AppBundle\Entity\geneTOpubmed":private]=> int(8894702) ["title":"AppBundle\Entity\geneTOpubmed":private]=> string(128) "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database." ["urltitle":"AppBundle\Entity\geneTOpubmed":private]=> string(126) "characterization-of-the-human-abc-superfamily-isolation-and-mapping-of-21-new-genes-using-the-expressed-sequence-tags-database" ["content":"AppBundle\Entity\geneTOpubmed":private]=> string(7374) " 8894702 1997 02 04 2017 12 13
0964-6906 5 10 1996 Oct Human molecular genetics Hum. Mol. Genet. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. 1649-55 As an approach to characterizing all human ATP-binding cassette (ABC) superfamily genes, a search of the human expressed sequence tag (EST) database was performed using sequences from known ABC genes. A total of 105 clones, containing sequences of potential ABC genes, were identified, representing 21 distinct genes. This brings the total number of characterized human ABC genes from 12 to 33. The new ABC genes were mapped by PCR on somatic cell and radiation hybrid panels and yeast artificial chromosomes (YACs). The genes are located on human chromosomes 1, 2, 3, 4, 6, 7, 10, 12, 13, 14, 16, 17 and X; at locations distinct from previously mapped members of the superfamily. The characterized genes display extensive diversity in sequence and expression pattern and this information was utilized to determine potential structural, functional and evolutionary relationships to previously characterized members of the ABC superfamily. Allikmets R R Laboratory of Viral Carcinogenesis, National Cancer Institute, Frederick Cancer Research and Development Center, MD 21702, USA. Gerrard B B Hutchinson A A Dean M M eng GENBANK U66672 U66692 Journal Article
England Hum Mol Genet 9208958 0964-6906 0 ATP-Binding Cassette Transporters IM ATP-Binding Cassette Transporters genetics Amino Acid Sequence Chromosome Mapping Databases, Factual Drug Resistance, Multiple genetics Humans Molecular Sequence Data Phylogeny Polymerase Chain Reaction Sequence Analysis
1996 10 1 1996 10 1 0 1 1996 10 1 0 0 ppublish 8894702
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