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ACER1: alkaline ceramidase 1

ALKCDase1, ASAH3

Summary

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010]

Organism: human (Homo sapiens)

ACER1 description

asah3 crispr knockout and activation products (m)

Catalog: sc-431351 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 ASAH3 CRISPR Knockout and Activation Products (m)  ASAH3 CRISPR Knockout and Activation Products (m)  ASAH3 CRISPR Knockout and Activation Products (m)  ASAH3 CRISPR Knockout and Activation Products (m)

mouse ASAH3-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

asah3 sirna (h), shrna and lentiviral particle gene silencers

Catalog: sc-97592 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 ASAH3 siRNA (h), shRNA and Lentiviral Particle Gene Silencers  ASAH3 siRNA (h), shRNA and Lentiviral Particle Gene Silencers  ASAH3 siRNA (h), shRNA and Lentiviral Particle Gene Silencers

human ASAH3-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

asah3 sirna (m), shrna and lentiviral particle gene silencers

Catalog: sc-141288 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 ASAH3 siRNA (m), shRNA and Lentiviral Particle Gene Silencers  ASAH3 siRNA (m), shRNA and Lentiviral Particle Gene Silencers  ASAH3 siRNA (m), shRNA and Lentiviral Particle Gene Silencers

mouse ASAH3-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

Acer1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV066959 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Acer1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV066955 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Acer1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV066957 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
E. coli, expression plasmid, clone: tracer1, mouse monoclonal antibody-, biotin Catalog: BMAtracer1B | Size: Ask | Price: Ask Supplier: accurate-monoclonals

Alternative name 1 E. coli, Expression Plasmid, Clone: tracer1, Mab anti-, Biotin Alternative name 2 E. coli, Expression Plasmid, Clone: tracer1, Mab antibody-, Biotin Alternative name 3 E. coli, Expression Plasmid, Clone: tracer1, Mab antibody-, Biotin
Acer1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV066954 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Acer1 antibody Catalog: GWB-MW079G | Size: 1 vial | Price: €625.56 Supplier: genways

Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Acer1 antibody Catalog: GWB-MW080H | Size: 1 vial | Price: €625.56 Supplier: genways

Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
E. coli, expression plasmid, clone: tracer1, mouse monoclonal antibody- Catalog: BMAtracer1 | Size: Ask | Price: Ask Supplier: accurate-monoclonals

Alternative name 1 E. coli, Expression Plasmid, Clone: tracer1, Mab anti- Alternative name 2 E. coli, Expression Plasmid, Clone: tracer1, Mab antibody- Alternative name 3 E. coli, Expression Plasmid, Clone: tracer1, Mab antibody-
Acer1 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV066956 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Acer1 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV066958 | Size: 1.0 µg DNA | Price: €720.42 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Acer1 over-expression lysate reagent Catalog: GWB-AAB12B | Size: 1 vial | Price: €555.92 Supplier: genways

Old catalog number 36-614-465575 Storage temperature store cold Expiry date 1 y
Anti-alkaline ceramidase 1 antibody Catalog: CPA3091-100ul | Size: 0,1 ml | Price: €530.71 Supplier: acr

Vial description Alkaline CDase 1, AlkCDase 1, ACER1, ASAH3 Category primary antibody Raised in Rabbit
Anti-alkaline ceramidase 1 antibody Catalog: CPA3091-200ul | Size: 0,2 ml | Price: €826.08 Supplier: acr

Vial description Alkaline CDase 1, AlkCDase 1, ACER1, ASAH3 Category primary antibody Raised in Rabbit
Anti-alkaline ceramidase 1 antibody Catalog: CPA3091-30ul | Size: 30 Вµl | Price: €391.43 Supplier: acr

Vial description Alkaline CDase 1, AlkCDase 1, ACER1, ASAH3 Category primary antibody Raised in Rabbit
Ceramidase elisa kit Catalog: E13650403 | Size: one plate of 96 wells per kit | Price: €804.47 Supplier: sincere

Long Name Human Ceramidase ELISA Kit Recognized antigen Ceramidase Species reactivity Human (Homo sapiens)
Acer1 antibody Catalog: 70R-10188 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Proteases, Inhibitors, & Enzymes
Acer1 antibody Catalog: 70R-10189 | Size: 50 µg | Price: €570.33 Supplier: fitzgerald

Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Proteases, Inhibitors, & Enzymes
Acer1 antibody Catalog: 70R-51410 | Size: 100 µl | Price: €644.78 Supplier: fitzgerald

Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Proteases, Inhibitors, & Enzymes
Acer1 blocking peptide Catalog: 33R-4174 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

Category Proteins Antibody Subtype Blocking Peptides Area of research Proteases, Inhibitors, & Enzymes
Acer1 blocking peptide Catalog: 33R-9701 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

Category Proteins Antibody Subtype Blocking Peptides Area of research Proteases, Inhibitors, & Enzymes
Guinea pig alkaline ceramidase 1(acer1) elisa kit Catalog: E05A1188 | Size: 96 well immunosorbent assay kit (48 available) | Price: €866.91 Supplier: BlueGen ELISAs

The ELISA's description ACER1 ELISA for Metabolism research Scientific field ACER1 ELISA for Metabolism research Domain Metabolism
Acer1 antibody - c-terminal region Catalog: ARP60812_P050 | Size: one vial | Price: €375.82 Supplier: aviva

Recognized antigen ACER1 - C-terminal region Product type Antibody Gene name ACER1
Acer1 antibody - c-terminal region Catalog: ARP60813_P050 | Size: one vial | Price: €375.82 Supplier: aviva

Recognized antigen ACER1 - C-terminal region Product type Antibody Gene name ACER1
Acer1 antibody - c-terminal region Catalog: OAAB14193 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen ACER1 - C-terminal region Product type Antibody Gene name ACER1
Acer1 antibody Catalog: OAAF03259 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen ACER1 Product type Antibody Gene name ACER1
Acer1 antibody - middle region Catalog: OASG00580 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen ACER1 - middle region Product type Antibody Gene name ACER1
Asah3 polyclonal antibody Catalog: ABP57363-30 | Size: 0,03 ml | Price: €336.2 Supplier: Abbkine

Antigen ASAH3 Clonality polyclonal antibody Raised in rabbit
Asah3 polyclonal antibody Catalog: ABP57363-100 | Size: 0,1 ml | Price: €523.51 Supplier: Abbkine

Antigen ASAH3 Clonality polyclonal antibody Raised in rabbit
Asah3 polyclonal antibody Catalog: ABP57363-200 | Size: 0,2 ml | Price: €742.03 Supplier: Abbkine

Antigen ASAH3 Clonality polyclonal antibody Raised in rabbit
Human acer1 crispr knock out 293t cell line Catalog: K0028651 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type 293T NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out 293 cell line Catalog: K0028652 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type 293 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out a549 cell line Catalog: K0028653 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type A549 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out hela cell line Catalog: K0028654 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type HeLa NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out mda-mb-435 cell line Catalog: K0028655 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type MDA-MB-435 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out hepg2 cell line Catalog: K0028656 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type HepG2 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out mcf7 cell line Catalog: K0028657 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type MCF7 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out k562 cell line Catalog: K0028658 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type K562 NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Human acer1 crispr knock out u87-mg cell line Catalog: K0028659 | Size: 1x10^6 cells/1.0ml | Price: €6989.27 Supplier: ABM CrispR

Cell line type U87-MG NCBI number NM_133492 Availability Please contact us every day to check the availability and/or to request a quote. For larger or bulk quantities a discount may apply.
Acer1 3'utr luciferase stable cell line Catalog: TU000158 | Size: 1 ml | Price: €1563.31 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #TU000158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Acer1 3'utr gfp stable cell line Catalog: TU050158 | Size: 1 ml | Price: €1563.31 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #TU050158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Acer1 3'utr lenti-reporter-luc virus Catalog: MV-h00158 | Size: 3 ml | Price: €769.65 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MV-h00158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Acer1 3'utr lenti-reporter-gfp virus Catalog: MV-h50158 | Size: 3 ml | Price: €769.65 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MV-h50158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Acer1 3'utr lenti-reporter-luc vector Catalog: MT-h00158 | Size: 1 ug | Price: €428.65 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MT-h00158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
Acer1 3'utr lenti-reporter-gfp vector Catalog: MT-h50158 | Size: 1 ug | Price: €428.65 Supplier: ABM microrna

Availability Please contact us every day between 9am-6pm local time to check the availability and/or to request a quote. For larger quantities a discount may apply. Ordering If you wish to order this product, please include the catalogue number #MT-h50158 in your purchase order among with your shipping and billing information. Technical file Please contact us to request the latest datasheet, protocol, certificate of analysis and SDS files.
uid :
125981

name :
ACER1

description :
alkaline ceramidase 1

chromosome :
19

geneticsource :
genomic

maplocation :
19p13.3

otheraliases :
ALKCDase1, ASAH3

otherdesignations :
alkaline ceramidase 1|CTB-180A7.3|N-acylsphingosine amidohydrolase (alkaline ceramidase) 3|N-acylsphingosine amidohydrolase 3|acylsphingosine deacylase 3|alkCDase 1|alkaline CDase 1

nomenclaturesymbol :
ACER1

nomenclaturename :
alkaline ceramidase 1

nomenclaturestatus :
Official

geneweight :
1092

chrsort :
19

chrstart :
6306141

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000019.10
chrstart: 6360367
chrstop: 6306141
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000019.10
chrstart: 6360358
chrstop: 6306141
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 6333276
chrstop: 6306126
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000019.10
chrstart: 6353443
chrstop: 6306141
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 6333276
chrstop: 6306126
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000019.10
chrstart: 6333628
chrstop: 6306498
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 6333276
chrstop: 6306126
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018930.2
chrstart: 6333276
chrstop: 6306126
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018930.1
chrstart: 6257748
chrstop: 6230619
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 6272429
chrstop: 6245302
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000019.9
chrstart: 6333639
chrstop: 6306509
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 6272429
chrstop: 6245302
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093293
chrstop: 6065538
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000019.8
chrstart: 6284561
chrstop: 6257724
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000062.1
chrstart: 6272351
chrstop: 6245517
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000151.1
chrstart: 6093215
chrstop: 6065753