Gen-script
All about genes

ABCC8: ATP binding cassette subfamily C member 8

ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Organism: human (Homo sapiens)

ABCC8 description

Abcc8 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV064889 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Abcc8 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV064886 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Abcc8 antibody Catalog: GWB-MP547G | Size: 1 vial | Price: €625.56 Supplier: genways

Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Abcc8 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV064884 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Abcc8 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV064888 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Sur1 antibody Catalog: bs-3641R | Size: 0.1ml | Price: €315.78 Supplier: Bioss Primary Unconjugated Antibodies

Long name SUR1 Primary Polyclonal Antibody Also known as SUR1 PAb Category Primary Antibodies
Abcc8 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV064885 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Abcc8 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV064887 | Size: 1.0 µg DNA | Price: €3419.11 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Sur1 positive controlfor western blot Catalog: PC-SUR1 | Size: 100 µg | Price: €317.71 Supplier: fabgen

Vial description purified SUR1 Positive Control Antibody's or peptide concentration ug/ml in stabilization buffer Raised in sterile environment
Sur1 blocking peptide sequence Catalog: P-SUR1 | Size: 100 µg | Price: €261.99 Supplier: fabgen

Vial description purified SUR1 Blocking Peptide Antibody's or peptide concentration ug/ml in stabilization buffer Raised in sterile environment
Anti-sur1 antibody fitc Catalog: SUR1-FITC | Size: 100 µg | Price: €547.52 Supplier: fabgen

Vial description purified SUR1 Antibody FITC Antibody's or peptide concentration ug/ml in stabilization buffer Raised in Rabbit
Anti-sur1 antibody biotin Catalog: SUR1-BIOTIN | Size: 100 µg | Price: €547.52 Supplier: fabgen

Vial description purified SUR1 Antibody BIOTIN Antibody's or peptide concentration ug/ml in stabilization buffer Raised in Rabbit
Anti-sur1 antibody Catalog: SUR1-101AP | Size: 100 µg | Price: €429.13 Supplier: fabgen

Vial description purified SUR1 Antibody Antibody's or peptide concentration ug/ml in stabilization buffer Raised in Rabbit
Abcc8 antibody Catalog: R33765-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Anti-abcc8 control peptide antibody Catalog: AP10332CP-N | Size: 0,1 mg | Price: €495.89 Supplier: acr

Vial description HRINS, SUR, SUR1, Sulfonylurea receptor 1 Category control peptide Raised in laboratory
Anti-abcc8 antibody Catalog: AP10332PU-N | Size: 0,1 mg | Price: €791.26 Supplier: acr

Vial description HRINS, SUR, SUR1, Sulfonylurea receptor 1 Category primary antibody Raised in Rabbit
Anti-abcc8 antibody Catalog: 42-749 | Size: 0.1 mg | Price: €216.13 Supplier: proscience

Gene names sulfonylurea receptor (hyperinsulinemia), ATP-binding cassette, sub-family C, member 8, TNDM2, SUR, PHHI, MRP8, HRINS, HI, HHF1, ABC36, sub-family C (CFTR/MRP), SUR1, ABCC8 Antibodie's label unlabelled serum Purity Antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abcc8 antibody Catalog: 70R-6686 | Size: 50 µg | Price: €614.76 Supplier: fitzgerald

Category Primary Antibody Antibody Subtype Polyclonal Antibodies, Purified Area of research Cell Biology
Abcc8 blocking peptide Catalog: 33R-7184 | Size: 100 µg | Price: €252.15 Supplier: fitzgerald

Category Proteins Antibody Subtype Blocking Peptides Area of research Cell Biology
Guinea pig atp-binding cassette sub-family c member 8(abcc8) elisa kit Catalog: E05A1143 | Size: 96 well immunosorbent assay kit (48 available) | Price: €866.91 Supplier: BlueGen ELISAs

The ELISA's description ABCC8 ELISA for signal Transduction research Scientific field ABCC8 ELISA for signal Transduction research Type of ELISA competitive ELISA
Abcc8 recombinant protein Catalog: OPCD01013 | Size: one vial | Price: €271.36 Supplier: aviva

Storage For short term storage ABCC8 Recombinant Protein may be kep at +4 deg. C. For long term storage keep the aliquoted vials frozen at -20 degrees Celsius. Tips Due to handling and transportation, small amounts of the ABCC8 Recombinant Protein may get caught on the walls or seal of the vials. Prior to use briefly rund the vial(s) through a centrifuge to collect all of the content on the bottom. Avoid freezing and thawing the vials numerous times as such cycles may denaturate the peptide chains and influence the item's performance. Alternative name ABCC8 recombinant Protein
Abcc8 antibody - n-terminal region Catalog: ARP43622_P050 | Size: one vial | Price: €375.82 Supplier: aviva

Recognized antigen ABCC8 - N-terminal region Product type Antibody Gene name ABCC8
Goat anti-sur1 / abcc8 antibody Catalog: OAEB02180 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen Goat SUR1 / ABCC8 Product type Antibody Gene name Goat SUR1 / ABCC8
Sur1 antibody Catalog: OASE00257 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen SUR1 Product type Antibody Gene name SUR1
Sur1 and sur2b antibody Catalog: OASE00280 | Size: one vial | Price: €509.1 Supplier: aviva

Recognized antigen SUR1 and SUR2B Product type Antibody Gene name SUR1 and SUR2B
Atp binding cassette transporter c8 (abcc8) elisa kit Catalog: SED628Hu | Size: 1 kit/96-well plate | Price: €974.97 Supplier: cclone

Short description of the assay Sandwich ELISA for determination of the concentration of ATP Binding Cassette Transporter C8 Antigen concentration that can be measured 1.25-20ng per ml Target antigen ATP Binding Cassette Transporter C8
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D | Size: 100 µg | Price: €417.84 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: Unconjugated
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A390 | Size: 100 µg | Price: €476.68 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 390
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A565 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 565
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A488 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 488
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A594 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 594
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A633 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 633
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A655 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 655
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A680 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 680
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-A700 | Size: 100 µg | Price: €475.48 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: ATTO 700
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-ALP | Size: 100 µg | Price: €468.27 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: Alkaline Phosphatase
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-APC | Size: 100 µg | Price: €474.28 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: APC
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-BI | Size: 100 µg | Price: €470.67 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: Biotin
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-FITC | Size: 100 µg | Price: €465.87 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: FITC
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-HRP | Size: 100 µg | Price: €461.07 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: HRP
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-P594 | Size: 100 µg | Price: €483.88 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: PE/ATTO 594
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-PCP | Size: 100 µg | Price: €474.28 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: PerCP
Mouse anti-rat sur1 monoclonal igg1, clone s289-16 Catalog: SMC-409D-RPE | Size: 100 µg | Price: €471.88 Supplier: StressMark antibodies

Clone S289-16 Immunogen Fusion protein amino acids 1548-1582 (cytoplasmic C-terminus) of rat SUR1 Antibody's full description Mouse Anti-Rat SUR1 Monoclonal IgG1 Antibody, Clone: S289-16: RPE
uid :
6833

name :
ABCC8

description :
ATP binding cassette subfamily C member 8

chromosome :
11

geneticsource :
genomic

maplocation :
11p15.1

otheraliases :
ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2

otherdesignations :
ATP-binding cassette sub-family C member 8|ATP-binding cassette transporter sub-family C member 8|ATP-binding cassette, sub-family C (CFTR/MRP), member 8|sulfonylurea receptor (hyperinsulinemia)|sulfonylurea receptor 1

nomenclaturesymbol :
ABCC8

nomenclaturename :
ATP binding cassette subfamily C member 8

nomenclaturestatus :
Official

geneweight :
27493

chrsort :
11

chrstart :
17392884

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000011.10
chrstart: 17476848
chrstop: 17392884
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000011.10
chrstart: 17476869
chrstop: 17392884
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 17498216
chrstop: 17414229
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000011.10
chrstart: 17476844
chrstop: 17392884
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 17498216
chrstop: 17414229
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000011.10
chrstart: 17476844
chrstop: 17392884
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182193
chrstop: 17098249
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 17498216
chrstop: 17414229
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018922.2
chrstart: 17498273
chrstop: 17414229
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018922.1
chrstart: 17422427
chrstop: 17338569
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 17628300
chrstop: 17544258
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000011.9
chrstart: 17498448
chrstop: 17414431
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 17628300
chrstop: 17544258
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000011.8
chrstart: 17455024
chrstop: 17371007
annotationrelease: 36.3
assemblyaccver: GCF_000002115.2
chraccver: AC_000054.1
chrstart: 17628300
chrstop: 17544258
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000143.1
chrstart: 17182250
chrstop: 17098249