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AAK1: AP2 associated kinase 1

Summary

Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Organism: human (Homo sapiens)

AAK1 description

aak1 antibody (lw-m11)

Catalog: sc-134242 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 AAK1 Antibody (LW-M11)  AAK1 Antibody (LW-M11)  AAK1 Antibody (LW-M11)

recommended for detection of AAK1 of human origin by WB, IP and ELISA

aak1 crispr knockout and activation products (m)

Catalog: sc-435372 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 AAK1 CRISPR Knockout and Activation Products (m)  AAK1 CRISPR Knockout and Activation Products (m)  AAK1 CRISPR Knockout and Activation Products (m)  AAK1 CRISPR Knockout and Activation Products (m)

mouse AAK1-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

aak1 sirna (h), shrna and lentiviral particle gene silencers

Catalog: sc-94850 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 AAK1 siRNA (h), shRNA and Lentiviral Particle Gene Silencers  AAK1 siRNA (h), shRNA and Lentiviral Particle Gene Silencers  AAK1 siRNA (h), shRNA and Lentiviral Particle Gene Silencers

human AAK1-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

aak1 sirna (m), shrna and lentiviral particle gene silencers

Catalog: sc-140731 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 AAK1 siRNA (m), shRNA and Lentiviral Particle Gene Silencers  AAK1 siRNA (m), shRNA and Lentiviral Particle Gene Silencers  AAK1 siRNA (m), shRNA and Lentiviral Particle Gene Silencers

mouse AAK1-specific siRNA, shRNA Plasmid and Lentiviral Particle gene silencers

aak1 crispr knockout and activation products (h)

Catalog: sc-406073 | Size: Ask | Price: Ask Supplier: Santa Cruz Biotechnology

 AAK1 CRISPR Knockout and Activation Products (h)  AAK1 CRISPR Knockout and Activation Products (h)  AAK1 CRISPR Knockout and Activation Products (h)  AAK1 CRISPR Knockout and Activation Products (h)

human AAK1-specific CRISPR/Cas9 KO Plasmid, HDR Plasmid, Double Nickase Plasmids, CRISPR Activation Plasmids and Lentiviral Activation Particles

Aak1 lentiviral vector (human) (cmv) (plenti-giii-cmv-c-term-ha) Catalog: LV064057 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Lkb1( aak1 dual inhibitor ) 5mg Catalog: A3556-5 | Size: 5mg | Price: €411.48 Supplier: Ape

This substance is also known as LKB1( AAK1 dual inhibitor ) 5 milligrams of pure chemical substance for laboratory research. This product has a molecular weight of g/mol 339.36 The molecular formula is C20H13N5O
Aak1 antibody Catalog: GWB-MT706D | Size: 1 vial | Price: €625.56 Supplier: genways

Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Aak1 lentiviral vector (human) (cmv) (plenti-giii-cmv) Catalog: LV064056 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Lkb1( aak1 dual inhibitor ) 50mg Catalog: A3556-50 | Size: 50mg | Price: €1298.08 Supplier: Ape

This substance is also known as LKB1( AAK1 dual inhibitor ) 50 milligrams of pure chemical substance for laboratory research. This product has a molecular weight of g/mol 339.36 The molecular formula is C20H13N5O
Aak1 antibody, alexa fluor 594 Catalog: bs-1507R-A594 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Long name AAK1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated Also known as Anti-AAK1 PAb ALEXA FLUOR 594 Category Conjugated Primary Antibodies
Lkb1( aak1 dual inhibitor ) 200mg Catalog: A3556-200 | Size: 200mg | Price: €2877.72 Supplier: Ape

This substance is also known as LKB1( AAK1 dual inhibitor ) 200 milligrams of pure chemical substance for laboratory research. This product has a molecular weight of g/mol 339.36 The molecular formula is C20H13N5O
Aak1 antibody, alexa fluor 488 Catalog: bs-1507R-A488 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Long name AAK1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated Also known as Anti-AAK1 PAb ALEXA FLUOR 488 Category Conjugated Primary Antibodies
Aak1 antibody, alexa fluor 647 Catalog: bs-1507R-A647 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Long name AAK1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated Also known as Anti-AAK1 PAb ALEXA FLUOR 647 Category Conjugated Primary Antibodies
Anti-aak1 antibody Catalog: A03A0005 | Size: 200ug (50ug, 100ug available) | Price: €558.33 Supplier: Bluegen antibodies

The antibodie's description anti-AP2-associated protein kinase 1, EC 2.7.11.1, Adaptor-associated kinase 1, AAK1, KIAA1048 antibody The antigen used epitope of the human, mouse, rat AP2-associated protein kinase 1, EC 2.7.11.1, Adaptor-associated kinase 1, AAK1, KIAA1048 antigen Gene name AP2-associated protein kinase 1, EC 2.7.11.1, Adaptor-associated kinase 1, AAK1, KIAA1048
Aak1 antibody, alexa fluor 555 Catalog: bs-1507R-A555 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Long name AAK1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated Also known as Anti-AAK1 PAb ALEXA FLUOR 555 Category Conjugated Primary Antibodies
Aak1 lentiviral vector (human) (ef1a) (plenti-giii-ef1a) Catalog: LV064061 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Aak1 lentiviral vector (human) (cmv) (plenti-giii-cmv-gfp-2a-puro) Catalog: LV064058 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Aak1 antibody, alexa fluor 350 Catalog: bs-1507R-A350 | Size: 100ul | Price: €399.53 Supplier: Bioss Primary Conjugated Antibodies. ALEXA FLUOR

Long name AAK1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated Also known as Anti-AAK1 PAb ALEXA FLUOR 350 Category Conjugated Primary Antibodies
Aak1 rabbit polyclonal antibody Catalog: SIG-4841 | Size: 0.1 mg | Price: €594.35 Supplier: Zyagen

Alternative name Aak1 production species: rabbit polyclonal (Antibody to) Gene target Aak1 Host Rabbit
Aak1 lentiviral vector (human) (ubc) (plenti-giii-ubc) Catalog: LV064060 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Aak1 antibody Catalog: GWB-MT707E | Size: 1 vial | Price: €625.56 Supplier: genways

Storage temperature store cold Expiry date 1 y Category research antibodies, ELISAs, recombinant proteins, vectors and reagents for laboratory use
Aak1 peptide Catalog: ZP-4841 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

Alternative name Aak1 short protein sequence Gene target Aak1 Peptide Technique peptide
Aak1 lentiviral vector (human) (cmv) (plenti-giii-cmv-rfp-2a-puro) Catalog: LV064059 | Size: 1.0 µg DNA | Price: €387.23 Supplier: ABM lentivectors

DNA lentivector for transduction information Lentiveral packaging plasmid DNA for non-viral plasmid transfection and direct use in plasmid expression. This DNA can alos be used for packaging into Lentiviral particles for high efficiency transduction and stably integrated expressions. GENTAUR suggests to use our ABM packaging mix LV003 of second generation virusses or the LV053, our 3rd Generation Packaging mixture. pLenti lentiviral plasmids DNAs are stored in 10milliMolar Tris/HCI with 1mM EDTA at a pH of 8 at -25 C. Vectors with selection markers like kanamycin, puromycin or cumate are available. Lentiviral technical files Lentivirus references
Lkb1( aak1 dual inhibitor ) 10mg Catalog: A3556-10 | Size: 10mg | Price: €514.5 Supplier: Ape

This substance is also known as LKB1( AAK1 dual inhibitor ) 10 milligrams of pure chemical substance for laboratory research. This product has a molecular weight of g/mol 339.36 The molecular formula is C20H13N5O
Aak1 peptide Catalog: ZP-4831 | Size: 0.05 mg | Price: €244.94 Supplier: Zyagen

Alternative name Aak1 short protein sequence Gene target Aak1 Peptide Technique peptide
Aak1 rabbit polyclonal antibody Catalog: SIG-4831 | Size: 0.1 mg | Price: €530.71 Supplier: Zyagen

Alternative name Aak1 production species: rabbit polyclonal (Antibody to) Gene target Aak1 Host Rabbit
Aak1 antibody Catalog: bs-1507R | Size: 0.1ml | Price: €315.78 Supplier: Bioss Primary Unconjugated Antibodies

Long name AAK1 Primary Polyclonal Antibody Also known as AAK1 PAb Category Primary Antibodies
Ap2 antibody Catalog: F47549-0.4ML | Size: 0.4 ml | Price: €487.48 Supplier: NJS poly

Category Antibody Concentration In 1X PBS, pH 7.4, with 0.09% sodium azide Form Antigen affinity purified
Aak1 antibody Catalog: R34135-100UG | Size: 0.1mg | Price: €487.48 Supplier: NJS poly

Category Antibody Concentration 0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide Form Antigen affinity purified
Aak1 antibody Catalog: F43998-0.08ML | Size: 0.08 ml | Price: €238.94 Supplier: NJS poly

Category Antibody Concentration In 1X PBS, pH 7.4, with 0.09% sodium azide Form Antigen affinity purified
Aak1 antibody Catalog: F43998-0.4ML | Size: 0.4 ml | Price: €487.48 Supplier: NJS poly

Category Antibody Concentration In 1X PBS, pH 7.4, with 0.09% sodium azide Form Antigen affinity purified
Anti-aak1 (c-term) antibody Catalog: AP14706PU-N | Size: 0,4 ml | Price: €704.81 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 (n-term) antibody Catalog: AP17859PU-N | Size: 0,4 ml | Price: €704.81 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 (c-term) antibody Catalog: AP22978PU-N | Size: 50 Вµg | Price: €878.91 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 (n-term) antibody Catalog: AP22987PU-N | Size: 50 Вµg | Price: €878.91 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 control peptide antibody Catalog: AP30002CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category control peptide Raised in laboratory
Anti-aak1 control peptide antibody Catalog: AP30003CP-N | Size: 50 Вµg | Price: €338.6 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category control peptide Raised in laboratory
Anti-ap2 antibody Catalog: AS12 2609 | Size: 50 Вµg | Price: €582.34 Supplier: acr

Vial description Floral homeotic protein APETALA 2) Category primary antibody Raised in Rabbit
Anti-aak1 antibody Catalog: C11150-1 | Size: 50 Вµg | Price: €416.64 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 antibody Catalog: C11150-2 | Size: 0,1 mg | Price: €600.35 Supplier: acr

Vial description AP2-associated protein kinase 1, KIAA1048 Category primary antibody Raised in Rabbit
Anti-aak1 antibody Catalog: 4831 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

Gene info Aak1 Antibody: AP2-associated protein kinase 1 (Aak1) is a member of the Ark1/Prk1 subfamily of Ser/Thr protein kinases that are thought to regulate endocytosis by phosphorylating the accessory endocytic components. Aak1 interacts with and phosphorylates the mu2 subunit of the AP-2 complex, which promotes binding of the AP-2 to tyrosine based (Yxxphi) internalization motif-containing receptors and subsequent receptor endocytosis. At least two isoforms of Aak1 are known to exist; the longer isoform contains an extended carboxy-terminus that contains an additional clathrin-binding domain. Overexpression of this long isoform or Aak1 depletion by RNA interference impairs transferrin recycling from the early/sorting endosome, suggesting that Aak1 functions at multiple steps of the endosomal pathway by regulating transferrin internalization and its recycling back to the plasma membrane. Gene names Aak1 Antibody: KIAA1048, AP2-associated protein kinase 1, Adaptor-associated kinase 1 Antibodie's label unlabelled serum
Anti-aak1 antibody Catalog: 4841 | Size: 0.02 mg, 0.1 mg | Price: €216.13 Supplier: proscience

Gene info Aak1 Antibody: AP2-associated protein kinase 1 (Aak1) is a member of the Ark1/Prk1 subfamily of Ser/Thr protein kinases that are thought to regulate endocytosis by phosphorylating the accessory endocytic components. Aak1 interacts with and phosphorylates the mu2 subunit of the AP-2 complex, which promotes binding of the AP-2 to tyrosine based (Yxxphi) internalization motif-containing receptors and subsequent receptor endocytosis. At least two isoforms of Aak1 are known to exist; the longer isoform contains an extended carboxy-terminus that contains an additional clathrin-binding domain. Overexpression of this long isoform or Aak1 depletion by RNA interference impairs transferrin recycling from the early/sorting endosome, suggesting that Aak1 functions at multiple steps of the endosomal pathway by regulating transferrin internalization and its recycling back to the plasma membrane. Gene names Aak1 Antibody: KIAA1048, AP2-associated protein kinase 1, Adaptor-associated kinase 1 Antibodie's label unlabelled serum
uid :
22848

name :
AAK1

description :
AP2 associated kinase 1

chromosome :
2

geneticsource :
genomic

maplocation :
2p13.3

otherdesignations :
AP2-associated protein kinase 1|adaptor-associated kinase 1

nomenclaturesymbol :
AAK1

nomenclaturename :
AP2 associated kinase 1

nomenclaturestatus :
Official

geneweight :
2590

chrsort :
02

chrstart :
69457994

annotationrelease: 109
assemblyaccver: GCF_000001405.38
chraccver: NC_000002.12
chrstart: 69643844
chrstop: 69457994
annotationrelease: 108
assemblyaccver: GCF_000001405.33
chraccver: NC_000002.12
chrstart: 69643844
chrstop: 69457994
annotationrelease: 108
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 69800611
chrstop: 69614736
annotationrelease: 107
assemblyaccver: GCF_000001405.28
chraccver: NC_000002.12
chrstart: 69643844
chrstop: 69457994
annotationrelease: 107
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 69800611
chrstop: 69614736
annotationrelease: 106
assemblyaccver: GCF_000001405.26
chraccver: NC_000002.12
chrstart: 69643844
chrstop: 69457994
annotationrelease: 106
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 106
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 69800611
chrstop: 69614736
annotationrelease: 105
assemblyaccver: GCF_000001405.25
chraccver: NC_000002.11
chrstart: 69901565
chrstop: 69685126
annotationrelease: 105
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 105
assemblyaccver: GCF_000306695.2
chraccver: NC_018913.2
chrstart: 69800611
chrstop: 69614736
annotationrelease: 104
assemblyaccver: GCF_000001405.22
chraccver: NC_000002.11
chrstart: 69870976
chrstop: 69685126
annotationrelease: 104
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 104
assemblyaccver: GCF_000306695.1
chraccver: NC_018913.1
chrstart: 69738056
chrstop: 69552113
annotationrelease: 103
assemblyaccver: GCF_000001405.21
chraccver: NC_000002.11
chrstart: 69870976
chrstop: 69685126
annotationrelease: 103
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 37.3
assemblyaccver: GCF_000001405.17
chraccver: NC_000002.11
chrstart: 69870976
chrstop: 69685126
annotationrelease: 37.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 37.2
assemblyaccver: GCF_000001405.14
chraccver: NC_000002.11
chrstart: 69870976
chrstop: 69685126
annotationrelease: 37.2
assemblyaccver: GCF_000002115.2
chraccver: AC_000045.1
chrstart: 69722073
chrstop: 69535199
annotationrelease: 37.2
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 37.1
assemblyaccver: GCF_000001405.13
chraccver: NC_000002.11
chrstart: 69870976
chrstop: 69685126
annotationrelease: 37.1
assemblyaccver: GCF_000002115.2
chraccver: AC_000045.1
chrstart: 69722073
chrstop: 69535199
annotationrelease: 37.1
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352
annotationrelease: 36.3
assemblyaccver: GCF_000001405.12
chraccver: NC_000002.10
chrstart: 69724480
chrstop: 69538630
annotationrelease: 36.3
assemblyaccver: GCF_000002125.1
chraccver: AC_000134.1
chrstart: 69607694
chrstop: 69421352